Development of mRNA vaccines against respiratory syncytial virus (RSV)

X Qiu, S Xu, Y Lu, Z Luo, Y Yan, C Wang, J Ji - Cytokine & Growth Factor …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that is the
primary etiologic pathogen of bronchitis and pneumonia in infants and the elderly. Currently …

[HTML][HTML] Respiratory syncytial virus vaccines: a review of the candidates and the approved vaccines

X Topalidou, AM Kalergis, G Papazisis - Pathogens, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is responsible for a significant proportion of global
morbidity and mortality affecting young children and older adults. In the aftermath of formalin …

Respiratory syncytial virus, recurrent wheeze and asthma: A narrative review of pathophysiology, prevention and future directions

E Binns, J Tuckerman, PV Licciardi… - Journal of Paediatrics …, 2022 - Wiley Online Library
Globally, respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and
pneumonia in young children, and the association between severe RSV disease and later …

Intranasal parainfluenza virus type 5 (PIV5)–vectored RSV vaccine is safe and immunogenic in healthy adults in a phase 1 clinical study

P Spearman, H Jin, K Knopp, P Xiao, MC Gingerich… - Science …, 2023 - science.org
Respiratory syncytial virus (RSV) can lead to serious disease in infants, and no approved
RSV vaccine is available for infants. This first in-human clinical trial evaluated a single dose …

RSV disease in infants and young children: Can we see a brighter future?

E Baraldi, G Checcucci Lisi, C Costantino… - Human Vaccines & …, 2022 - Taylor & Francis
Respiratory syncytial virus (RSV) is a highly contagious seasonal virus and the leading
cause of Lower Respiratory Tract Infections (LRTI), including pneumonia and bronchiolitis in …

Bridging nanoplatform and vaccine delivery, a landscape of strategy to enhance nasal immunity

Z Teng, LY Meng, JK Yang, Z He, XG Chen… - Journal of Controlled …, 2022 - Elsevier
Vaccination is an urgently needed and effective option to address epidemic, cancers,
allergies, and other diseases. Nasal administration of vaccines offers many benefits over …

Health care-associated infections in older adults: epidemiology and prevention

BL Tesini, G Dumyati - Infectious Disease Clinics, 2023 - id.theclinics.com
Age-associated physiologic changes, unique geriatric syndromes, and frequent, prolonged
health care interactions make older adults uniquely vulnerable to infections. The …

[HTML][HTML] Respiratory syncytial virus: knowledge, attitudes and beliefs of general practitioners from North-Eastern Italy (2021)

M Riccò, P Ferraro, S Peruzzi, A Zaniboni, S Ranzieri - Pediatric reports, 2022 - mdpi.com
Respiratory syncytial virus (RSV) is a lead cause of morbidity and hospitalizations in infants.
RSV vaccines are currently under development, and preventive options are limited to …

Implications of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic on the epidemiology of pediatric respiratory syncytial virus infection

OA Odumade, SD van Haren… - Clinical Infectious …, 2022 - academic.oup.com
Respiratory viral infections account for a large percentage of global disease and death.
Respiratory syncytial virus is a seasonal virus affecting immunologically vulnerable …

[HTML][HTML] Respiratory syncytial virus: new challenges for molecular epidemiology surveillance and vaccination strategy in patients with ILI/SARI

F Tramuto, CM Maida, D Di Naro, G Randazzo, F Vitale… - Vaccines, 2021 - mdpi.com
Several respiratory pathogens are responsible for influenza-like illness (ILI) and severe
respiratory infections (SARI), among which human respiratory syncytial virus (hRSV) …