An accessible alternative to melarsomine:“moxi-doxy” for treatment of adult heartworm infection in dogs

LS Jacobson, BA DiGangi - Frontiers in Veterinary Science, 2021 - frontiersin.org
Canine heartworm infection, caused by the filarial parasite Dirofilaria immitis, represents a
serious and expanding animal welfare concern that is expected to increase due to the …

Heartworm adulticide treatment: a tropical perspective

F Dantas-Torres, J Ketzis, G Pérez Tort, AD Mihalca… - Parasites & vectors, 2023 - Springer
Dirofilaria immitis (the canine heartworm) is widespread in the tropics, with prevalence
surpassing 30% in high-risk areas. In addition to the suitable climatic conditions that favour …

[HTML][HTML] Elimination of Dirofilaria immitis infection in dogs, Linosa island, Italy, 2020–2022

E Brianti, E Napoli, G De Benedetto… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Abstract On Linosa Island, Italy, Dirofilaria immitis infection has been hyperendemic in dogs
and seroprevalent among islanders. In 2020, we implemented a heartworm disease …

Treatment with doxycycline is associated with complete clearance of circulating Wolbachia DNA in Dirofilaria immitis-naturally infected dogs

VN Louzada-Flores, L Kramer, E Brianti, E Napoli… - Acta Tropica, 2022 - Elsevier
Bacteria of the genus Wolbachia are endosymbionts of parasitic filarial nematodes,
including Dirofilaria immitis, and are a target for the treatment of canine heartworm disease …

Prevalence of Dirofilaria immitis in shelter dogs in Bucaramanga metropolitan area, Colombia

AAF Muñoz, AR Martinez, JC Pinilla - Veterinary Parasitology: Regional …, 2020 - Elsevier
The heartworm Dirofilaria immitis is the causative agent of cardiopulmonary dirofilariosis in
dogs and cats and also infects humans. The current knowledge about this parasite in South …

False positive antigen test for Dirofilaria immitis after heat treatment of the blood sample in a microfilaremic dog infected with Acanthocheilonema dracunculoides

V Szatmári, MW van Leeuwen, CJ Piek, L Venco - Parasites & Vectors, 2020 - Springer
Background Dirofilaria immitis is responsible for heartworm disease in dogs in endemic
areas worldwide. Screening for this infection is done by blood tests. Antigen testing is the …

Non-Arsenical heartworm adulticidal therapy using topical moxidectin-imidacloprid and doxycycline: a prospective case series

MK Ames, P VanVranken, C Evans, CE Atkins - Veterinary parasitology, 2020 - Elsevier
This prospective case series evaluated the adulticidal efficacy of topical 10%
moxidectin/2.5% imidacloprid (M/I; Advantage Multi®, Bayer, Shawnee Mission, KS, USA) …

Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?

JD Turner, AE Marriott, D Hong, P O'Neill, SA Ward… - Veterinary …, 2020 - Elsevier
Filarial nematodes are tissue-dwelling parasitic worms that can cause a range of disfiguring
pathologies in humans and potentially lethal infections of companion animals. The bacterial …

New molecular entities and structure–activity relationships of drugs designed by the natural product derivatization method from 2010 to 2018

Q Cui, R Bian, F Xu, Q Li, W Wang, Q Bian - Studies in Natural Products …, 2021 - Elsevier
An important concept, the natural product derivatization method, was introduced and defined
to comprehensively evaluate the significance of natural product derivatization in the design …

Serodiagnostic difficulties and possibilities of heartworm disease in regions where both Dirofilaria immitis and Dirofilaria repens infections …

Z Becker, N Holló, R Farkas, M Gyurkovszky… - Acta Veterinaria …, 2022 - akjournals.com
This retrospective study was performed on 71 dogs which had been admitted for heartworm
screening or with clinical suspicion of heartworm disease. The examination methods …