The effects of carbon nanotubes on lung and dermal cellular behaviors
S Luanpitpong, L Wang, Y Rojanasakul - Nanomedicine, 2014 - Future Medicine
Carbon nanotubes (CNTs) hold great promise to create new and better products, but their
adverse health effect is a major concern. Human exposure to CNTs is primarily through …
adverse health effect is a major concern. Human exposure to CNTs is primarily through …
Total glucosides of danggui Buxue Tang attenuate BLM‐induced pulmonary fibrosis via regulating oxidative stress by inhibiting NOX4
P Zhao, WC Zhou, DL Li, XT Mo, L Xu… - Oxidative Medicine …, 2015 - Wiley Online Library
Pulmonary fibrosis (PF) is a serious chronic lung disease with unknown pathogenesis.
Researches have confirmed that oxidative stress which is regulated by NADPH oxidase‐4 …
Researches have confirmed that oxidative stress which is regulated by NADPH oxidase‐4 …
P120-catenin regulates pulmonary fibrosis and TGF-β induced lung fibroblast differentiation
Y Zhang, H Jiao, Y Wu, X Sun - Life sciences, 2019 - Elsevier
Abstract P120-catenin (P120) was known to function in adhesion between cells and signal
transduction in many types of cells. In this study, we investigated the expression and role of …
transduction in many types of cells. In this study, we investigated the expression and role of …
[HTML][HTML] Ubiquitination and deubiquitination emerge as players in idiopathic pulmonary fibrosis pathogenesis and treatment
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease that is associated with
aberrant activation of TGF-β, myofibroblast differentiation, and abnormal extracellular matrix …
aberrant activation of TGF-β, myofibroblast differentiation, and abnormal extracellular matrix …
[HTML][HTML] Mammalian neuraminidases in immune-mediated diseases: mucins and beyond
Mammalian neuraminidases (NEUs), also known as sialidases, are enzymes that cleave off
the terminal neuraminic, or sialic, acid resides from the carbohydrate moieties of glycolipids …
the terminal neuraminic, or sialic, acid resides from the carbohydrate moieties of glycolipids …
Iguratimod ameliorates bleomycin‐induced alveolar inflammation and pulmonary fibrosis in mice by suppressing expression of matrix metalloproteinase‐9
L Zhao, B Mu, R Zhou, Y Cheng… - International journal of …, 2019 - Wiley Online Library
Aim To investigate the potential therapeutic efficacy of iguratimod (IGU) on bleomycin (BLM)‐
induced pulmonary fibrosis in mice. Methods A total of 75 C57BL/6 mice were randomly and …
induced pulmonary fibrosis in mice. Methods A total of 75 C57BL/6 mice were randomly and …
[HTML][HTML] Tanshinone ⅡA attenuates bleomycin-induced pulmonary fibrosis in rats
H He, H Tang, L Gao, Y Wu… - Molecular …, 2015 - spandidos-publications.com
Idiopathic pulmonary fibrosis is a chronic and progressive fibrotic lung disorder with
unknown etiology and a high mortality rate. Tanshinone ⅡA (Tan ⅡA) is a lipophilic …
unknown etiology and a high mortality rate. Tanshinone ⅡA (Tan ⅡA) is a lipophilic …
[HTML][HTML] Role of MicroRNAs in Signaling Pathways Associated with the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Focus on Epithelial-Mesenchymal Transition
AR Cadena-Suárez… - International Journal of …, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease with high mortality
and unclear etiology. Previous evidence supports that the origin of this disease is associated …
and unclear etiology. Previous evidence supports that the origin of this disease is associated …
[HTML][HTML] Cell-penetrating peptides selectively targeting SMAD3 inhibit profibrotic TGF-β signaling
TGF-β is considered a master switch in the pathogenesis of organ fibrosis. The primary
mediators of this activity are the SMAD proteins, particularly SMAD3. In the current study, we …
mediators of this activity are the SMAD proteins, particularly SMAD3. In the current study, we …
[HTML][HTML] Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells
F Wirsdörfer, F Cappuccini, M Niazman, S de Leve… - Radiation …, 2014 - Springer
Background Lymphocyte infiltration is a common feature of radiation-induced pneumonitis
and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we …
and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we …