Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids

AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …

Discovery of plant-derived anti-tumor natural products: Potential leads for anti-tumor drug discovery

Z Hui, H Wen, J Zhu, H Deng, X Jiang, XY Ye… - Bioorganic …, 2023 - Elsevier
Natural products represent a paramount source of novel drugs. Numerous plant-derived
natural products have demonstrated potent anti-tumor properties, thereby garnering …

Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges

P Kumbhar, A Manjappa, R Shah, NK Jha… - Journal of Controlled …, 2022 - Elsevier
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …

Pharmacological activities and molecular mechanisms of Pulsatilla saponins

J Zhong, L Tan, M Chen, C He - Chinese Medicine, 2022 - Springer
Saponins are found in a variety of higher plants and display a wide range of
pharmacological activities, including expectorant, anti-inflammatory, vasoprotective and …

Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin

FC Cadoná, RF Dantas, GH de Mello… - Critical Reviews in …, 2022 - Taylor & Francis
Natural products have been studied to reveal new therapies against human dysfunctions
since they present several medicinal properties. Caffeine, theobromine and (+)-catechin are …

Bioactive components, pharmacological effects, and drug development of traditional herbal medicine Rubus chingii Hu (Fu-Pen-Zi)

B He, L Dai, L Jin, Y Liu, X Li, M Luo, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Rubus chingii Hu (Chinese Raspberry), known as Fu-Pen-Zi in Chinese, a woody perennial
plant of the genus Rubus in the Rosaceae family, has specific nutritional and medicinal …

[HTML][HTML] New trends in the practical use of isoquinoline alkaloids as potential drugs applicated in infectious and non-infectious diseases

T Tuzimski, A Petruczynik - Biomedicine & Pharmacotherapy, 2023 - Elsevier
In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …

Floral phytochemistry: impact of volatile organic compounds and nectar secondary metabolites on pollinator behavior and health

F Slavković, A Bendahmane - Chemistry & Biodiversity, 2023 - Wiley Online Library
Plants produce a plethora of phytochemicals including sugars, amino acids (AAs), volatile
organic compounds (VOCs) and secondary metabolites (SMs) with different ecological …

Immune effect of active components of traditional Chinese medicine on triple-negative breast cancer

W Zhao, J Liu, Y Li, Z Chen, D Qi… - Frontiers in pharmacology, 2021 - frontiersin.org
Triple-negative breast cancers are heterogeneous, poorly prognostic, and metastatic
malignancies that result in a high risk of death for patients. Targeted therapy for triple …