Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins

MS Lee, SJ Bensinger - Cellular & molecular immunology, 2022 - nature.com
Cholesterol is a critical lipid for all mammalian cells, ensuring proper membrane integrity,
fluidity, and biochemical function. Accumulating evidence indicates that macrophages …

Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis

AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …

Functionalized polystyrene nanoplastic-induced energy homeostasis imbalance and the immunomodulation dysfunction of marine clams (Meretrix meretrix) at …

L Liu, H Zheng, L Luan, X Luo, X Wang, H Lu… - Environmental …, 2021 - pubs.rsc.org
The toxic mechanisms of functionalized polystyrene nanoplastics (NPs) in bivalves,
especially regarding energy homeostasis and immunity in benthic marine ecosystem, are …

Diverse functions of apolipoprotein AI in lung fibrosis

M Wygrecka, I Alexopoulos… - American Journal of …, 2023 - journals.physiology.org
Apolipoprotein AI (apoA-I) mediates reverse cholesterol transport (RCT) out of cells. In
addition to its important role in the RTC, apoA-I also possesses anti-inflammatory and …

Viral modulation of lipid rafts and their potential as putative antiviral targets

YJ Gee, YL Sea, SK Lal - Reviews in Medical Virology, 2023 - Wiley Online Library
Lipid rafts are ubiquitous in cells. They are identified as cholesterol and glycosphingolipid
enriched microdomains on cellular membranes. They serve as platforms for cellular …

A current update on the role of HDL-based nanomedicine in targeting macrophages in cardiovascular disease

A Rani, G Marsche - Pharmaceutics, 2023 - mdpi.com
High-density lipoproteins (HDL) are complex endogenous nanoparticles involved in
important functions such as reverse cholesterol transport and immunomodulatory activities …

Probiotic effector compounds: Current knowledge and future perspectives

EBM Daliri, FK Ofosu, C Xiuqin, R Chelliah… - Frontiers in …, 2021 - frontiersin.org
Understanding the mechanism behind probiotic action will enable a rational selection of
probiotics, increase the chances of success in clinical studies and make it easy to …

High-density lipoproteins: a role in inflammation in COPD

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a widespread disease associated with
high rates of disability and mortality. COPD is characterized by chronic inflammation in the …

The role of ABC transporters in lipid metabolism and the comorbid course of chronic obstructive pulmonary disease and atherosclerosis

S Kotlyarov, A Kotlyarova - International Journal of Molecular Sciences, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) ranks among the leading causes of
morbidity and mortality worldwide. COPD rarely occurs in isolation and is often combined …

Vitamin D counteracts lipid accumulation, augments free fatty acid-induced ABCA1 and CPT-1A expression while reducing CD36 and C/EBPβ protein levels in …

M Marino, S Venturi, C Del Bo', P Møller, P Riso… - Biomedicines, 2022 - mdpi.com
The biologically active form of vitamin D, calcitriol (VD3), has received great attention for its
extraskeletal effects, such as a protective role on the cardiovascular system. The aim of the …