Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins
MS Lee, SJ Bensinger - Cellular & molecular immunology, 2022 - nature.com
Cholesterol is a critical lipid for all mammalian cells, ensuring proper membrane integrity,
fluidity, and biochemical function. Accumulating evidence indicates that macrophages …
fluidity, and biochemical function. Accumulating evidence indicates that macrophages …
Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis
AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …
leads to various life-threatening cardiovascular complications. However, no effective …
Functionalized polystyrene nanoplastic-induced energy homeostasis imbalance and the immunomodulation dysfunction of marine clams (Meretrix meretrix) at …
L Liu, H Zheng, L Luan, X Luo, X Wang, H Lu… - Environmental …, 2021 - pubs.rsc.org
The toxic mechanisms of functionalized polystyrene nanoplastics (NPs) in bivalves,
especially regarding energy homeostasis and immunity in benthic marine ecosystem, are …
especially regarding energy homeostasis and immunity in benthic marine ecosystem, are …
Diverse functions of apolipoprotein AI in lung fibrosis
M Wygrecka, I Alexopoulos… - American Journal of …, 2023 - journals.physiology.org
Apolipoprotein AI (apoA-I) mediates reverse cholesterol transport (RCT) out of cells. In
addition to its important role in the RTC, apoA-I also possesses anti-inflammatory and …
addition to its important role in the RTC, apoA-I also possesses anti-inflammatory and …
Viral modulation of lipid rafts and their potential as putative antiviral targets
Lipid rafts are ubiquitous in cells. They are identified as cholesterol and glycosphingolipid
enriched microdomains on cellular membranes. They serve as platforms for cellular …
enriched microdomains on cellular membranes. They serve as platforms for cellular …
A current update on the role of HDL-based nanomedicine in targeting macrophages in cardiovascular disease
High-density lipoproteins (HDL) are complex endogenous nanoparticles involved in
important functions such as reverse cholesterol transport and immunomodulatory activities …
important functions such as reverse cholesterol transport and immunomodulatory activities …
Probiotic effector compounds: Current knowledge and future perspectives
Understanding the mechanism behind probiotic action will enable a rational selection of
probiotics, increase the chances of success in clinical studies and make it easy to …
probiotics, increase the chances of success in clinical studies and make it easy to …
High-density lipoproteins: a role in inflammation in COPD
S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a widespread disease associated with
high rates of disability and mortality. COPD is characterized by chronic inflammation in the …
high rates of disability and mortality. COPD is characterized by chronic inflammation in the …
The role of ABC transporters in lipid metabolism and the comorbid course of chronic obstructive pulmonary disease and atherosclerosis
S Kotlyarov, A Kotlyarova - International Journal of Molecular Sciences, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) ranks among the leading causes of
morbidity and mortality worldwide. COPD rarely occurs in isolation and is often combined …
morbidity and mortality worldwide. COPD rarely occurs in isolation and is often combined …
Vitamin D counteracts lipid accumulation, augments free fatty acid-induced ABCA1 and CPT-1A expression while reducing CD36 and C/EBPβ protein levels in …
The biologically active form of vitamin D, calcitriol (VD3), has received great attention for its
extraskeletal effects, such as a protective role on the cardiovascular system. The aim of the …
extraskeletal effects, such as a protective role on the cardiovascular system. The aim of the …