Biochemical properties and roles of DprA protein in bacterial natural transformation, virulence, and pilin variation

DK Sharma, HS Misra, SC Bihani… - Journal of …, 2023 - Am Soc Microbiol
Natural transformation enables bacteria to acquire DNA from the environment and
contributes to genetic diversity, DNA repair, and nutritional requirements. DNA processing …

Sentinel cells programmed to respond to environmental DNA including human sequences

XA Nou, CA Voigt - Nature Chemical Biology, 2024 - nature.com
Monitoring environmental DNA can track the presence of organisms, from viruses to
animals, but requires continuous sampling of transient sequences from a complex milieu …

Adaptive evolution of hybrid bacteria by horizontal gene transfer

JJ Power, F Pinheiro, S Pompei… - Proceedings of the …, 2021 - National Acad Sciences
Horizontal gene transfer (HGT) is an important factor in bacterial evolution that can act
across species boundaries. Yet, we know little about rate and genomic targets of cross …

Genome-wide transformation reveals extensive exchange across closely related Bacillus species

M Förster, I Rathmann, M Yüksel… - Nucleic Acids …, 2023 - academic.oup.com
Bacterial transformation is an important mode of horizontal gene transfer that helps spread
genetic material across species boundaries. Yet, the factors that pose barriers to genome …

Plant organellar MSH1 is a displacement loop–specific endonuclease

A Peñafiel-Ayala, A Peralta-Castro… - Plant And Cell …, 2024 - academic.oup.com
Abstract MutS HOMOLOG 1 (MSH1) is an organellar-targeted protein that obstructs ectopic
recombination and the accumulation of mutations in plant organellar genomes. MSH1 also …

[HTML][HTML] Programming bacteria for multiplexed DNA detection

YY Cheng, Z Chen, X Cao, TD Ross, TG Falbel… - Nature …, 2023 - nature.com
DNA is a universal and programmable signal of living organisms. Here we develop cell-
based DNA sensors by engineering the naturally competent bacterium Bacillus subtilis (B …

Sequence similarity network and protein structure prediction offer insights into the evolution of microbial pathways for ferrous iron oxidation

L Li, Z Liu, D Meng, Y Liu, T Liu, C Jiang, H Yin - Msystems, 2023 - Am Soc Microbiol
Dissimilatory ferrous iron [Fe (II)] oxidation is a well-established microbial energy generation
strategy. This study aims to comprehensively investigate the distribution and evolution of …

Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation

R Torres, E Serrano, JC Alonso - Nucleic Acids Research, 2019 - academic.oup.com
During natural transformation Bacillus subtilis RecA, polymerized onto the incoming single-
stranded (ss) DNA, catalyses DNA strand invasion resulting in a displacement loop (D-loop) …

Bacillus subtilis DisA regulates RecA-mediated DNA strand exchange

R Torres, B Carrasco, C Gándara… - Nucleic acids …, 2019 - academic.oup.com
Bacillus subtilis diadenylate cyclase DisA converts two ATPs into c-di-AMP, but this activity is
suppressed upon interaction with sites of DNA damage. DisA forms a rapid moving focus …

Recombination proteins differently control the acquisition of homeologous DNA during Bacillus subtilis natural chromosomal transformation

E Serrano, C Ramos, JC Alonso… - Environmental …, 2021 - Wiley Online Library
Natural chromosomal transformation (CT) plays a major role in prokaryote evolution, yet
factors that govern the integration of DNA from related species remain poorly understood …