Enterococci are unusually well adapted for survival and persistence in a variety of adverse
environments, including on inanimate surfaces in the hospital environment and at sites of …

Enterococci, traditionally viewed as Gram-positive commensal bacteria inhabiting the
alimentary canals of humans and animals, are now acknowledged to be organisms capable …

Enterococcus faecalis and Enterococcus faecium are common inhabitants of the human
gastrointestinal tract, as well as frequent opportunistic pathogens. Enterococci cause a …

Animal infection models in the pharmacokinetic/pharmacodynamic (PK/PD) evaluation of
antimicrobial therapy serve an important role in preclinical assessments of new antibiotics …

With the emergence of multiply resistant Staphylococcus aureus, there is an urgent need to
better understand the molecular determinants of S. aureus pathogenesis. A model of …

The in vitro activity of LY 146032, a cyclic lipopeptide antibiotic belonging to the class of
agents designated A21978C, was compared with those of vancomycin, cefpirome …

Infective endocarditis (IE) is a life-threatening infective disease with increasing incidence
worldwide. From early on, in the antibiotic era, it was recognized that high-dose and long …

Enterococci are hardy, gram-positive cocci that are common residents of the gastrointestinal
tracts of nearly all land animals, including humans. While a core member of the microbiome …

Clinical studies performed by us and others have found an association between slime
production and strains of coagulase-negative staphylococci that infect indwelling medical …

Isogenic strains of Staphylococcus aureus, differing in fibronectin binding, were constructed
for studies of the contribution of fibronectin binding to the in vivo pathogenesis of …