Cyclin-dependent kinases in breast cancer: expression pattern and therapeutic implications

S Sofi, U Mehraj, H Qayoom, S Aisha, SMB Asdaq… - Medical oncology, 2022 - Springer
Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …

Phytochemistry, Pharmacology, and Toxicology of Datura Species—A Review

M Sharma, I Dhaliwal, K Rana, AK Delta, P Kaushik - Antioxidants, 2021 - mdpi.com
Datura, a genus of medicinal herb from the Solanaceae family, is credited with toxic as well
as medicinal properties. The different plant parts of Datura sp., mainly D. stramonium L …

Tropane alkaloids (hyoscyamine, scopolamine and atropine) from genus Datura: Extractions, contents, syntheses and effects

Z Shi, W Zou, Z Zhu, Z Xiong, S Li, P Dong… - Industrial Crops and …, 2022 - Elsevier
Belonging to family Solanaceae, genus Datura is widely distributed all over the world and
famous for its narcosis and acesodyne in ancient China. And Datura is also annoying due to …

Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders

BA Bhat, A Almilaibary, RA Mir, BM Aljarallah… - Frontiers in …, 2022 - frontiersin.org
The current scientific community is facing a daunting challenge to unravel reliable natural
compounds with realistic potential to treat neurological disorders such as Alzheimer's …

Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya

WR Mir, BA Bhat, MA Rather, S Muzamil… - Scientific reports, 2022 - nature.com
Geranium wallichianum D. Don ex Sweet is a well-known medicinal plant in Kashmir
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …

Chemical analysis of Iranian Rosa damascena essential oil, concrete, and absolute oil under different bio-climatic conditions

M Yaghoobi, MM Farimani, Z Sadeghi, S Asghari… - Industrial Crops and …, 2022 - Elsevier
Rosa damascena Mill., the unique species of Rosaceae, is one of the valuable medicinal
and ornamental aromatic plants cultivated in different parts of Iran. Climatic conditions …

Cryptolepine targets TOP2A and inhibits tumor cell proliferation in breast cancer cells-an in vitro and in silico study

U Mehraj, H Qayoom, S Shafi… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: DNA Topoisomerase II Alpha (TOP2A), a protein-coding gene, is central to the
replication process and has been found deregulated in several malignancies, including …

Identification and analysis of dysregulated fatty acid metabolism genes in breast cancer subtypes

U Yousuf, S Sofi, A Makhdoomi, MA Mir - Medical Oncology, 2022 - Springer
Breast cancer is one of the most aggressive and lethal types of transformation among
women. An anomaly of normal fatty acid metabolism is acknowledged as a critical trigger for …

Essential oil, flavonoids and anthocyanins profiling of some Iranian damask rose (Rosa damascena Mill.) genotypes

H Ahadi, M Shokrpour, R Fatahi, MR Naghavi… - Industrial Crops and …, 2023 - Elsevier
Increasing production efficiency is necessary for the industrialization of plant cultivation
which includes the type and content of metabolites in medicinal and aromatic plants. In the …

In vitro and in silico evaluation of antimicrobial properties of Delphinium cashmerianum L., a medicinal herb growing in Kashmir, India

BA Bhat, WR Mir, BA Sheikh, MA Rather… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Microorganisms are developing resistance to synthetic
drugs. As a result, the search for novel antimicrobial compounds has become an urgent …