Microtubules are critical for a variety of important functions in eukaryotic cells. During
intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the …

Biomolecular condensates, regardless of whether they exhibit liquid-like properties, are in
many cases not fully amorphous, but instead exhibit partial degrees of local structure and …

Background Glioma is one of the most aggressive malignant brain tumors that is
characterized with inevitably infiltrative growth and poor prognosis. ARST is a novel lncRNA …

The physical properties of cytoskeletal microtubules have a multifaceted effect on the
expression of their cellular functions. A superfamily of microtubule-associated proteins …

Development is a complex process that occurs throughout the life cycle. F-actin, a major
component of the cytoskeleton, is essential for the morphogenesis of tissues and organs …

Scar formation resulting from burns or severe trauma can significantly compromise the
structural integrity of skin and lead to permanent loss of skin appendages, ultimately …

The oral cavity harbors approximately 1,000 microbial species, and both pathogenic and
commensal strains are involved in the development of carcinogenesis by stimulating chronic …

Gliomas are heterogeneous neoplasms, classified into grade I to IV according to their
malignancy and the presence of specific histological/molecular hallmarks. The higher grade …

Although it is known that majority of kinesin motors walk predominantly toward the plus end
of microtubules (MTs) in a hand-over-hand manner, the structural origin of the stepping …

Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases
(IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal …