The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Crossing the blood-brain barrier: advances in nanoparticle technology for drug delivery in neuro-oncology

AM Hersh, S Alomari, BM Tyler - International journal of molecular …, 2022 - mdpi.com
The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Development of polymeric nanoparticles for blood–brain barrier transfer—strategies and challenges

W Zhang, A Mehta, Z Tong, L Esser… - Advanced …, 2021 - Wiley Online Library
Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …

Micro-and nano-plastics in marine environment: Source, distribution and threats—A review

L Peng, D Fu, H Qi, CQ Lan, H Yu, C Ge - Science of the total environment, 2020 - Elsevier
Plastic litters have become the predominant components of marine debris due to extensive
consumption plastics and mismanagement of plastic wastes. As part of the problem …

[HTML][HTML] Magnetic iron oxide nanoparticles for brain imaging and drug delivery

R Qiao, C Fu, H Forgham, I Javed, X Huang… - Advanced Drug Delivery …, 2023 - Elsevier
Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

[HTML][HTML] Polystyrene nanoparticles: Sources, occurrence in the environment, distribution in tissues, accumulation and toxicity to various organisms

K Kik, B Bukowska, P Sicińska - Environmental Pollution, 2020 - Elsevier
Civilization development is associated with the use of plastic. When plastic was introduced
to the market, it was assumed that it was less toxic than glass. Recently, it is known that …

Reactive oxygen species‐regulating strategies based on nanomaterials for disease treatment

C Zhang, X Wang, J Du, Z Gu, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway

R Shen, K Yang, X Cheng, C Guo, X Xing, H Sun… - Environmental …, 2022 - Elsevier
The environmental pollution from microplastics has caused concern from the whole society
due to its harm to organisms. However, the effect of microplastics on liver damage and …