Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …

The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP
synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has …

Mitochondrial complex III (CIII2) and complex IV (CIV), which can associate into a higher-
order supercomplex (SC III2+ IV), play key roles in respiration. However, structures of these …

Ever since its discovery, the double-stranded DNA contained in the mitochondria of
eukaryotes has fascinated researchers because of its bacterial endosymbiotic origin, crucial …

Plant mitochondria play a major role during respiration by producing the ATP required for
metabolism and growth. ATP is produced during oxidative phosphorylation (OXPHOS), a …

The majority of the pyruvate inside plant mitochondria is either transported into the matrix
from the cytosol via the mitochondria pyruvate carrier (MPC) or synthesized in the matrix by …

Background Diabetic peripheral neuropathy (DPN) is a common complication of diabetes
lacking efficient treatment. Magnolol (MG), a peroxisome proliferator-activated receptor γ …

Mitochondria are central organelles for respiration in plants. At the heart of this process is
oxidative phosphorylation (OXPHOS) system, which generates ATP required for cellular …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer type with poor
prognosis due to its high metastatic potential, however, the role of metabolic reprogramming …

Background Oxidative stress (OS) and mitochondrial alterations have been implicated in the
pathogenesis of rheumatoid arthritis (RA). Various environmental triggers like air pollutants …