[HTML][HTML] Progress in the mechanism and targeted drug therapy for COPD

C Wang, J Zhou, J Wang, S Li, A Fukunaga… - Signal transduction and …, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

Oxidative stress and free radicals in COPD–implications and relevance for treatment

W Domej, K Oettl, W Renner - International journal of chronic …, 2014 - Taylor & Francis
Oxidative stress occurs when free radicals and other reactive species overwhelm the
availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and …

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

BR Celli, W MacNee, A Agusti… - European …, 2004 - Eur Respiratory Soc
Background The Standards for the Diagnosis and Treatment of Patients with COPD
document 2004 updates the position papers on chronic obstructive pulmonary disease …

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung …

RA Pauwels, AS Buist, PMA Calverley… - American journal of …, 2001 - atsjournals.org
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive
Pulmonary Disease | NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) …

[PDF][PDF] Indoor air pollution in developing countries: a major environmental and public health challenge

N Bruce, R Perez-Padilla… - Bulletin of the World …, 2000 - SciELO Public Health
Around 50% of people, almost all in developing countries, rely on coal and biomass in the
form of wood, dung and crop residues for domestic energy. These materials are typically …

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

J Kim, YN Cha, YJ Surh - Mutation Research/Fundamental and Molecular …, 2010 - Elsevier
Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a key transcription factor that plays a
central role in cellular defense against oxidative and electrophilic insults by timely induction …

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

PJ Barnes, SD Shapiro… - European Respiratory …, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease is a leading cause of death and disability, but has
only recently been extensively explored from a cellular and molecular perspective. There is …

Systemic effects of chronic obstructive pulmonary disease

AGN Agusti, A Noguera, J Sauleda… - European …, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is characterised by an inappropriate/
excessive inflammatory response of the lungs to respiratory pollutants, mainly tobacco …

Complex chronic comorbidities of COPD

LM Fabbri, F Luppi, B Beghé… - European Respiratory …, 2008 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is defined by fixed airflow limitation
associated with an abnormal pulmonary and systemic inflammatory response of the lungs to …

An official American Thoracic Society/European Respiratory Society statement: research questions in chronic obstructive pulmonary disease

BR Celli, M Decramer, JA Wedzicha… - American journal of …, 2015 - atsjournals.org
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …