Ankylosing spondylitis: an autoimmune or autoinflammatory disease?
Ankylosing spondylitis (AS) is a chronic inflammatory disorder of unknown aetiology. Unlike
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …
Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis
E Gracey, A Burssens, I Cambré, G Schett… - Nature reviews …, 2020 - nature.com
Mechanical loading is an important factor in musculoskeletal health and disease. Tendons
and ligaments require physiological levels of mechanical loading to develop and maintain …
and ligaments require physiological levels of mechanical loading to develop and maintain …
Axial spondyloarthritis: concept, construct, classification and implications for therapy
PC Robinson, S van der Linden, MA Khan… - Nature Reviews …, 2021 - nature.com
The axial spondyloarthritis (axSpA) disease concept has undergone substantial change
from when the entity ankylosing spondylitis was defined by the modified New York criteria in …
from when the entity ankylosing spondylitis was defined by the modified New York criteria in …
Data-driven definitions for active and structural MRI lesions in the sacroiliac joint in spondyloarthritis and their predictive utility
Objectives To determine quantitative SI joint MRI lesion cut-offs that optimally define a
positive MRI for inflammatory and structural lesions typical of axial SpA (axSpA) and that …
positive MRI for inflammatory and structural lesions typical of axial SpA (axSpA) and that …
The bone marrow side of axial spondyloarthritis
Spondyloarthritis (SpA) is characterized by the infiltration of innate and adaptive immune
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
Nonsteroidal antiinflammatory drugs and susceptibility to COVID‐19
JS Chandan, DT Zemedikun… - Arthritis & …, 2021 - Wiley Online Library
Objective To identify whether active use of nonsteroidal antiinflammatory drugs (NSAIDs)
increases susceptibility to developing suspected or confirmed coronavirus disease 2019 …
increases susceptibility to developing suspected or confirmed coronavirus disease 2019 …
The role of imaging in the diagnosis and management of axial spondyloarthritis
WP Maksymowych - Nature Reviews Rheumatology, 2019 - nature.com
MRI of the sacroiliac joints is increasingly acknowledged as being indispensable in the early
diagnosis of axial spondyloarthritis (axSpA) and as having a prominent role in the prognosis …
diagnosis of axial spondyloarthritis (axSpA) and as having a prominent role in the prognosis …
Frequency of MRI changes suggestive of axial spondyloarthritis in the axial skeleton in a large population-based cohort of individuals aged< 45 years
Objective To investigate the frequency of bone marrow oedema (BME) and fatty lesions (FL)
suggestive of axial spondyloarthritis (axSpA) on MRI of the spine and sacroiliac joints (SIJ) …
suggestive of axial spondyloarthritis (axSpA) on MRI of the spine and sacroiliac joints (SIJ) …
High prevalence of spondyloarthritis-like MRI lesions in postpartum women: a prospective analysis in relation to maternal, child and birth characteristics
T Renson, A Depicker, AS De Craemer… - Annals of the …, 2020 - ard.bmj.com
Objectives Bone marrow oedema (BMO) on MRI of sacroiliac joints (SIJs) represents a
hallmark of axial spondyloarthritis (SpA), yet such lesions may also occur under augmented …
hallmark of axial spondyloarthritis (SpA), yet such lesions may also occur under augmented …
Progressive increase in sacroiliac joint and spinal lesions detected on magnetic resonance imaging in healthy individuals in relation to age
T Renson, M de Hooge, AS De Craemer… - Arthritis & …, 2022 - Wiley Online Library
Objective Magnetic resonance imaging (MRI) plays a pivotal role in spondyloarthritis (SpA)
diagnosis. However, a detailed description of MRI findings of the sacroiliac (SI) joints and …
diagnosis. However, a detailed description of MRI findings of the sacroiliac (SI) joints and …