Obesity‐related glomerulopathy: Current approaches and future perspectives

JI Martínez‐Montoro, E Morales… - Obesity …, 2022 - Wiley Online Library
Obesity‐related glomerulopathy (ORG) is a silent comorbidity which is increasing in
incidence as the obesity epidemic escalates. ORG is associated with serious health …

Obesity and diabetic kidney disease

C Maric-Bilkan - Medical Clinics, 2013 - medical.theclinics.com
The prevalence of obesity (body mass index [BMI] 30 kg/m2) has risen to epidemic
proportions and continues to be a major health problem worldwide. 1–3 The high …

[HTML][HTML] Protection of mitochondria prevents high-fat diet–induced glomerulopathy and proximal tubular injury

HH Szeto, S Liu, Y Soong, N Alam, GT Prusky… - Kidney international, 2016 - Elsevier
Obesity is a major risk factor for the development of chronic kidney disease, even
independent of its association with hypertension, diabetes, and dyslipidemia. The primary …

Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity

G Sun, Z Yin, N Liu, X Bian, R Yu, X Su, B Zhang… - Biochemical and …, 2017 - Elsevier
Emerging evidence shows that obesity induces renal injury and is an independent risk factor
for the development of chronic kidney disease (CKD), even without diabetes or …

Obesity and chronic kidney disease: a current review

S Nawaz, R Chinnadurai, S Al‐Chalabi… - Obesity Science & …, 2023 - Wiley Online Library
Background Obesity poses significant challenges to healthcare globally, particularly through
its bi‐directional relationship with co‐morbid metabolic conditions such as type 2 diabetes …

The role of the renin-angiotensin-aldosterone system in obesity-related renal diseases

C Rüster, G Wolf - Seminars in nephrology, 2013 - Elsevier
Obesity is an independent risk factor for the development and progression of chronic kidney
disease and one of the emerging reasons for end-stage renal disease owing to its dramatic …

The role of chronic inflammation in obesity‐associated cancers

ME Ramos-Nino - International Scholarly Research Notices, 2013 - Wiley Online Library
There is a strong relationship between metabolism and immunity, which can become
deleterious under conditions of metabolic stress. Obesity, considered a chronic inflammatory …

Renal and cardiovascular outcomes after weight loss from gastric bypass surgery in type 2 diabetes: cardiorenal risk reductions exceed atherosclerotic benefits

V Liakopoulos, S Franzén, AM Svensson… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE We examined detailed renal and cardiovascular (CV) outcomes after gastric
bypass (GBP) surgery in people with obesity and type 2 diabetes mellitus (T2DM), across …

Molecular mechanisms underlying the potential antiobesity‐related diseases effect of cocoa polyphenols

F Ali, A Ismail, S Kersten - Molecular nutrition & food research, 2014 - Wiley Online Library
Obesity and related metabolic diseases (eg, type 2 diabetes, cardiovascular diseases, and
hypertension) are the most prevailing nutrition‐related issues in the world. An emerging …

Adipokines promote chronic kidney disease

C Rüster, G Wolf - Nephrology Dialysis Transplantation, 2013 - academic.oup.com
The rapid growth in obesity worldwide contributes to an increase in metabolic syndrome and
obesity-related kidney disease with an enhanced increased risk for chronic kidney disease …