Chemically modified biopolymers for the formation of biomedical hydrogels

VG Muir, JA Burdick - Chemical reviews, 2020 - ACS Publications
Biopolymers are natural polymers sourced from plants and animals, which include a variety
of polysaccharides and polypeptides. The inclusion of biopolymers into biomedical …

From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases

EH Pilkington, EJA Suys, NL Trevaskis, AK Wheatley… - Acta biomaterialia, 2021 - Elsevier
Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …

[HTML][HTML] Supramolecular assemblies based on natural small molecules: Union would be effective

Y Hou, L Zou, Q Li, M Chen, H Ruan, Z Sun, X Xu… - Materials Today Bio, 2022 - Elsevier
Natural products have been used to prevent and treat human diseases for thousands of
years, especially the extensive natural small molecules (NSMs) such as terpenoids, steroids …

A journey of challenges and victories: a bibliometric worldview of nanomedicine since the 21st century

J Wang, W Zhao, Z Zhang, X Liu, T Xie… - Advanced …, 2024 - Wiley Online Library
Nanotechnology profoundly affects the advancement of medicine. Limitations in diagnosing
and treating cancer and chronic diseases promote the growth of nanomedicine. However …

Direct exosome quantification via bivalent-cholesterol-labeled DNA anchor for signal amplification

F He, H Liu, X Guo, BC Yin, BC Ye - Analytical chemistry, 2017 - ACS Publications
Exosomes, as an important subpopulation of extracellular vesicles (EVs), play an important
role in intercellular communications in various important pathophysiological processes …

A fluorescence assay for exosome detection based on bivalent cholesterol anchor triggered target conversion and enzyme-free signal amplification

X Wang, H Shang, C Ma, L Chen - Analytical Chemistry, 2021 - ACS Publications
Exosomes are emerging as one of the most promising biomarkers for early disease
diagnosis and prognosis. The significant challenges facing the available methods include …

Pulmonary siRNA delivery for lung disease: review of recent progress and challenges

L Ding, S Tang, TA Wyatt, DL Knoell… - Journal of controlled …, 2021 - Elsevier
Lung diseases are a leading cause of mortality worldwide and there exists urgent need for
new therapies. Approval of the first siRNA treatments in humans has opened the door for …

Review of the advances in lipid anchors-based biosensors for the isolation and detection of exosomes

J Zheng, X Hu, Y Zeng, B Zhang, Z Sun, X Liu… - Analytica Chimica …, 2023 - Elsevier
Exosomes are nanoparticles with a bilayer lipid structure that carry cargo from their cells of
origin. These vesicles are vital to disease diagnosis and therapeutics; however …

Facile layer-by-layer self-assembly toward enantiomeric poly (lactide) stereocomplex coated magnetite nanocarrier for highly tunable drug deliveries

Z Li, D Yuan, G Jin, BH Tan, C He - ACS applied materials & …, 2016 - ACS Publications
A highly tunable nanoparticle (NP) system with multifunctionalities was developed as drug
nanocarrier via a facile layer-by-layer (LbL) stereocomplex (SC) self-assembly of …

Targeted delivery of epirubicin to tumor-associated macrophages by sialic acid-cholesterol conjugate modified liposomes with improved antitumor activity

S Zhou, T Zhang, B Peng, X Luo, X Liu, L Hu… - International journal of …, 2017 - Elsevier
With the knowledge that the receptors of sialic acid are overexpressed on the surface of
tumor-associated macrophages (TAMs), which play a crucial role in the tumor's progression …