The immunological and genetic basis of inflammatory bowel disease

G Bouma, W Strober - Nature reviews immunology, 2003 - nature.com
The inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, are chronic
inflammatory disorders of the gastrointestinal tract. Enormous progress has been made …

The genetics and immunopathogenesis of inflammatory bowel disease

JH Cho - Nature Reviews Immunology, 2008 - nature.com
Genome-wide association studies efficiently and powerfully assay common genetic
variation. The application of these studies to Crohn's disease has provided insight into the …

Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease: prevalence and …

JF Quinton, B Sendid, D Reumaux, P Duthilleul… - Gut, 1998 - gut.bmj.com
Background—Perinuclear antineutrophil cytoplasmic autoantibodies (pANCA) are a well
recognised marker for ulcerative colitis. Antibodies to oligomannosidic epitopes of the yeast …

[HTML][HTML] Etiopathogenesis of inflammatory bowel diseases

S Danese, C Fiocchi - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Theories explaining the etiopathogenesis of inflammatory bowel disease (IBD) have been
proposed ever since Crohn's disease (CD) and ulcerative colitis (UC) were recognized as …

[图书][B] Chemical and functional properties of food components

ZE Sikorski - 2006 - taylorfrancis.com
Water, saccharides, proteins, lipids, minerals, colorants, and additives all contribute to the
nutritional value and sensory properties of food. During post harvest storage and …

Air pollution: An environmental factor contributing to intestinal disease

LA Beamish, AR Osornio-Vargas… - Journal of Crohn's and …, 2011 - academic.oup.com
The health impacts of air pollution have received much attention and have recently been
subject to extensive study. Exposure to air pollutants such as particulate matter (PM) has …

The genetics of psoriasis: a complex disorder of the skin and immune system

J Bhalerao, AM Bowcock - Human molecular genetics, 1998 - academic.oup.com
In the last few years, molecular genetics analyses have permitted novel insights into
psoriasis, a disease characterized by uncontrolled proliferation of keratinocytes and …

Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics

EA Vasiliauskas, LY Kam, LC Karp, J Gaiennie, H Yang… - Gut, 2000 - gut.bmj.com
BACKGROUND Perinuclear antineutrophil cytoplasmic antibodies (pANCA) have been
detected in a clinically distinct Crohn's disease subpopulation. Antibodies to Saccharomyces …

Johne's Disease, Inflammatory Bowel Disease, and Mycobacterium paratuberculosis

O Chacon, LE Bermudez, RG Barletta - Annu. Rev. Microbiol., 2004 - annualreviews.org
▪ Abstract Johne's disease is a chronic diarrhea affecting all ruminants. Mycobacterium
avium subsp. paratuberculosis (MAP), a slowly growing mycobacteria, is the etiologic agent …

Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1

JH Cho, DL Nicolae, LH Gold… - Proceedings of the …, 1998 - National Acad Sciences
The idiopathic inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis
(UC), are chronic, frequently disabling diseases of the intestines. Segregation analyses, twin …