The pathogenesis and potential therapeutic targets in sepsis

W Zhang, H Jiang, G Wu, P Huang, H Wang, H An… - MedComm, 2023 - Wiley Online Library
Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …

Cross-talk between the cytokine IL-37 and thyroid hormones in modulating chronic inflammation associated with target organ damage in age-related metabolic and …

LT Majnarić, Z Bosnić, M Štefanić… - International Journal of …, 2022 - mdpi.com
Chronic inflammation is considered to be the main mechanism contributing to the
development of age-related metabolic and vascular conditions. The phases of chronic …

Endoplasmic reticulum peroxynitrite fluctuations in hypoxia-induced endothelial injury and sepsis with a two-photon fluorescence probe

Z Zhan, L Chai, H Yang, Y Dai, Z Wei… - Analytical …, 2023 - ACS Publications
Sepsis is a serious systemic inflammatory disease that frequently results in death. Early
diagnosis and timely targeted interventions could improve the therapeutic effect. Recent …

Plantamajoside alleviates acute sepsis-induced organ dysfunction through inhibiting the TRAF6/NF-κB axis

D Feng, R Guo, W Liao, J Li, S Cao - Pharmaceutical Biology, 2023 - Taylor & Francis
Context Plantamajoside (PMS) possesses rich pharmacological characteristics that have
been applied to remedy dozens of diseases. However, the understanding of PMS in sepsis …

Biochemical Significance of miR-155 and miR-375 as Diagnostic Biomarkers and Their Correlation with the NF-κβ/TNF-α Axis in Breast Cancer

SA Abdel-Samed, WG Hozyen, SM Shaaban… - Indian Journal of Clinical …, 2024 - Springer
Serum microRNAs (miRs) have recently been proposed as potential cancer biomarkers for
early detection. Thyroid hormones play a crucial role in human health, and their alterations …

[HTML][HTML] Association between obstructive sleep apnea and thyroid function: a 10-year retrospective study

Y Shi, Z Cao, Y Xie, Y Yuan, X Chen, Y Su, X Niu, H Liu… - Sleep Medicine, 2023 - Elsevier
Purpose To explore whether the obstructive sleep apnea (OSA) has an impact on thyroid
function in patients. Method The data of 853 patients were retrospectively collected from the …

The potential of thyroid hormone therapy in severe COVID-19: rationale and preliminary evidence

I Mourouzis, V Apostolaki, A Trikas, L Kokkinos… - International Journal of …, 2022 - mdpi.com
Tissue hypoxia is one of the main pathophysiologic mechanisms in sepsis and particularly in
COVID-19. Microvascular dysfunction, endothelialitis and alterations in red blood cell …

[HTML][HTML] 低T3 综合征对心力衰竭患者预后的影响

关琳, 王传合, 孙志军 - 中国医科大学学报, 2022 - html.rhhz.net
目的探讨低T3 综合征对慢性心力衰竭(简称心衰) 患者临床预后的影响. 方法回顾性分析慢性心
衰患者7 780 例, 根据患者入院后检测的甲状腺功能, 将其分为低T3 综合征组和甲状腺功能正常 …

[HTML][HTML] 生命早期因素与饮食相关行为对小学生超重, 肥胖的影响

张宁馨, 丁雅洁, 刘洋, 魏薇, 孙琦, 贾丽红 - 中国医科大学学报, 2022 - html.rhhz.net
目的探讨生命早期因素与饮食相关行为对小学生超重, 肥胖的影响. 方法选取沈阳市大东区2
所小学1 736 名在校学生作为研究对象, 检测学生身高, 体质量并进行发育早期因素和饮食相关 …

Influence of carvedilol and thyroid hormones on inflammatory proteins and cardioprotective factor HIF-1α in the infarcted heart

VD Ortiz, RB Teixeira, P Türck… - Canadian Journal of …, 2023 - cdnsciencepub.com
Inflammatory pathways of Toll-like receptor 4 (TLR4) and NLRP3 inflammasome contribute
to acute myocardial infarction (AMI) pathophysiology. The hypoxia‐inducible factor 1α (HIF …