Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application

M Vaghari-Tabari, S Moein, A Alipourian, D Qujeq… - Biochimie, 2023 - Elsevier
Inflammatory bowel disease is a chronic inflammatory disease and has periods of
recurrence and remission. Improper immune responses to gut flora bacteria, along with …

[HTML][HTML] Abnormal blood bacteriome, gut dysbiosis, and progression to severe dengue disease

W Chancharoenthana, S Kamolratanakul… - Frontiers in Cellular …, 2022 - frontiersin.org
Despite a well-known association between gut barrier defect (leaky gut) and several
diseases, data on translocation of pathogen molecules, including bacterial DNA (blood …

Targeting immune cell metabolism in the treatment of inflammatory bowel disease

V Zaiatz Bittencourt, F Jones, G Doherty… - Inflammatory bowel …, 2021 - academic.oup.com
The cells of the immune system are highly dynamic, constantly sensing and adapting to
changes in their surroundings. Complex metabolic pathways govern leukocytes' ability to …

Dysregulation of metabolic pathways in circulating natural killer cells isolated from inflammatory bowel disease patients

V Zaiatz Bittencourt, F Jones, M Tosetto… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims Inflammatory bowel diseases [IBD], comprising Crohn's
disease [CD] and ulcerative colitis [UC], are chronic conditions characterized by severe …

[HTML][HTML] NK cells contribute to reovirus-induced IFN responses and loss of tolerance to dietary antigen

PH Brigleb, E Kouame, KL Fiske, GM Taylor… - JCI insight, 2022 - ncbi.nlm.nih.gov
Celiac disease is an immune-mediated intestinal disorder that results from loss of oral
tolerance (LOT) to dietary gluten. Reovirus elicits inflammatory Th1 cells and suppresses …

[HTML][HTML] Innate lymphoid cells as regulators of epithelial integrity: therapeutic implications for inflammatory bowel diseases

A Schulz-Kuhnt, MF Neurath, S Wirtz, I Atreya - Frontiers in Medicine, 2021 - frontiersin.org
The occurrence of epithelial defects in the gut relevantly contributes to the pathogenesis of
inflammatory bowel diseases (IBD), whereby the impairment of intestinal epithelial barrier …

[HTML][HTML] New insights and implications of natural killer cells in Parkinson's disease

KB Menees, JK Lee - Journal of Parkinson's Disease, 2022 - content.iospress.com
Parkinson's disease (PD) is the second most common neurodegenerative disease and is
characterized by the loss of dopaminergic neurons in the substantia nigra and the abnormal …

[HTML][HTML] Early life inoculation with adult-derived microbiota accelerates maturation of intestinal microbiota and enhances NK cell activation in broiler chickens

N Meijerink, JG Kers, FC Velkers… - Frontiers in Veterinary …, 2020 - frontiersin.org
Studies in mammals, including chickens, have shown that the development of the immune
system is affected by interactions with intestinal microbiota. Early life microbial colonization …

[HTML][HTML] Analysis of gut microbiome profiles in common marmosets (Callithrix jacchus) in health and intestinal disease

A Sheh, SC Artim, MA Burns, JA Molina-Mora… - Scientific reports, 2022 - nature.com
Chronic gastrointestinal (GI) diseases are the most common diseases in captive common
marmosets. To understand the role of the microbiome in GI diseases, we characterized the …

[HTML][HTML] Precision postbiotics and mental health: the management of post-COVID-19 complications

M Pandey, A Bhati, K Priya, KK Sharma… - Probiotics and …, 2022 - Springer
The health catastrophe originated by COVID-19 pandemic construed profound impact on a
global scale. However, a plethora of research studies corroborated convincing evidence …