Background Natural killer (NK) cells represent a critical component of the innate immune
system's response against cancer and viral infections, among other diseases. To distinguish …

NK cells are defined as the major components of the immunological network which exerts
defense against tumors and viral infections as well as regulation of innate and adaptive …

Background Altered intestinal permeability and low-grade chronic inflammation disrupt the
integrity of the blood–brain barrier (microbiota–gut–brain axis), probably playing a role in the …

Purpose Ulcerative colitis (UC) is a chronic inflammatory immune-related disease.
Imbalance between pathogenic cells and immunosuppressive cells is associated with …

Inflammatory bowel disease (IBD), which include Crohn's disease (CD) and ulcerative colitis
(UC), exhibits a complex multifactorial pathogenesis involving genetic susceptibility …

Background: The pathogenesis of ulcerative colitis (UC) is closely related to immunity. The
immune characteristic differences between active UC (UCa) and inactive UC (UCin) have …

Introduction Children born by cesarean section (CS) are at a greater risk of inflammatory
bowel disease (IBD). However, the mechanisms underlying the association are not yet well …

Tissue resident (TR) immune cells play important roles in facilitating tissue homeostasis,
coordinating immune responses against infections and tumors, and maintaining …

The mucosal immune system plays a vital role in protecting the host from the external
environment. Its major challenge is to balance immune responses against harmful and …

Gut microbes are immunologically tolerated in the gastrointestinal tract but trigger
aggressive immune responses upon translocation across the gut barrier. Although oral …