Covalent inhibitors of glycosidases and their applications in biochemistry and biology

BP Rempel, SG Withers - Glycobiology, 2008 - academic.oup.com
Glycoside hydrolases are important enzymes in a number of essential biological processes.
Irreversible inhibitors of this class of enzyme have attracted interest as probes of both …

Glycosidases: a key to tailored carbohydrates

P Bojarová, V Křen - Trends in biotechnology, 2009 - cell.com
In recent years, carbohydrate-processing enzymes have become the enzymes of choice in
many applications thanks to their stereoselectivity and efficiency. This review presents …

Activity-based proteomics probes for carbohydrate-processing enzymes: current trends and future outlook

KA Stubbs - Carbohydrate research, 2014 - Elsevier
Carbohydrate-processing enzymes are gaining more attention due to their roles in health
and disease as these enzymes are involved in the construction and deconstruction of vast …

A general method for affinity-based proteomic profiling of exo-α-glycosidases

MN Gandy, AW Debowski, KA Stubbs - Chemical Communications, 2011 - pubs.rsc.org
A general method for affinity-based proteomic profiling of exo -α-glycosidases - Chemical
Communications (RSC Publishing) DOI:10.1039/C1CC10308C Royal Society of Chemistry View …

Specificity Fingerprinting of Retaining β‐1,4‐Glycanases in the Cellulomonas fimi Secretome Using Two Fluorescent Mechanism‐Based Probes

O Hekmat, C Florizone, YW Kim, LD Eltis… - …, 2007 - Wiley Online Library
Functional proteomics methods are crucial for activity‐and mechanism‐based investigation
of enzymes in biological systems at a post‐translational stage. Glycosidases have central …

[PDF][PDF] Cyclophellitol analogues for profiling of exo-and endo-glycosidases

SP Schröder - 2018 - scholarlypublications …
2.1 Introduction lycosidases are responsible for the cleavage of glycosidic linkages and are
key in the turnover of glycans and glycoconjugates–a large and highly diverse class of …