The random forest approach combined with spherically symmetric design was applied to
optimize the water extraction and alcohol precipitation extraction process of Astragalus …

Scope. The neuroprotective properties of the antidiabetic plant Garcinia kola have been
reported. Here, we performed a motor sign prevention‐guided fractionation of G. kola extract …

Brain-derived neurotrophic factor signaling via its receptor tropomyosin receptor kinase B
regulates several crucial physiological processes. It has been shown to act in the brain …

The immediate early gene Arc is a master regulator of synaptic function and a critical
determinant of memory consolidation. Here, we show that Arc interacts with dynamic …

Objective To examine the neuroanatomical substrates underlying the effects of minocycline
in alleviating lipopolysaccharide (LPS)-induced neuroinflammation. Methods Forty C57BL/6 …

Diabetes is one of the crucial health problems in this decade. Insulin secreted by β cells in
the pancreatic islets of Langerhans plays a critical role in regulating the blood glucose level …

Detection of slight changes in the chemical, thermal, and physical environments of the
ocular surface is necessary to protect eyesight. The cornea, as the most densely innervated …

Diabetes mellitus (DM), a chronic metabolic disorder, may induce neurophysiological and
structural changes in the central nervous system (ie, diabetic encephalopathy). Diabetic …

Neuroprotection represents a challenge in the research and development (R&D) of drugs
aimed to treat retinal degenerative diseases. Neuroprotective therapeutic strategies may …

The diabetic peripheral neuropathy pain model was constructed after 95 Sprague Dawley
rats had been randomly divided among blank reference and model groups. Aescin low-dose …