African swine fever, caused by African swine fever virus (ASFV), is a highly contagious and
fatal disease that poses a significant threat to the global pig industry. The limited information …

BACKGROUND: Aortic stenosis (AS) is driven by progressive inflammatory and fibrocalcific
processes regulated by circulating inflammatory and valve resident endothelial and …

Background Dysregulation of the B-cell activating factor (BAFF) system is involved in the
pathogenesis of systemic lupus erythematosus (SLE). Increased serum concentrations of …

Abstract BAFF, APRIL and BAFF-R are key proteins involved in the development of B-
lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were …

Autoimmune disease is a substantial cause of morbidity and is strongly influenced by
genetic risk. Extensive efforts have characterized the overall genetic basis of many …

Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease with
numerous clinical manifestations. Organ involvement can aggravate patients with SLE and …

Introduction Glioblastoma multiforme (GBM) is one of the most aggressive types of brain
cancer, and despite rigorous research, patient prognosis remains poor. The characterization …

During the last decade, important advances have occurred regarding understanding of the
pathogenesis and treatment of rheumatoid arthritis (RA). Nevertheless, response to …

Background Because of the increasing incidence and overall burden of systemic lupus
erythematosus (SLE), efforts have been made to identify the factors that contribute to SLE …

Objective Single cell profiling of synovial tissue has previously identified gene signatures
associated with rheumatoid arthritis (RA) pathophysiology, but synovial tissue is difficult to …