Role of proprioceptors in chronic musculoskeletal pain

CH Lee, CC Chen - Experimental Physiology, 2024 - Wiley Online Library
Proprioceptors are non‐nociceptive low‐threshold mechanoreceptors. However, recent
studies have shown that proprioceptors are acid‐sensitive and express a variety of proton …

Genetic exploration of roles of acid‐sensing ion channel subtypes in neurosensory mechanotransduction including proprioception

YC Lin, CH Lee, JY Sung, CC Chen - Experimental Physiology, 2024 - Wiley Online Library
Although acid‐sensing ion channels (ASICs) are proton‐gated ion channels responsible for
sensing tissue acidosis, accumulating evidence has shown that ASICs are also involved in …

[HTML][HTML] When sng meets acupuncture--a paradigm-shift biomarker for translational research

WZ Sun, CC Chen, JG Lin - Journal of Traditional and Complementary …, 2024 - Elsevier
The sensation of sng (pronounced/səŋ/, the Romanization form of 痠 or soreness in
Taiwanese Southern Min) associated with de qi, a composite of unique sensations, is a …

[HTML][HTML] The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation

E Budusan, CD Payne, TI Gonzalez… - Biochemical …, 2024 - Elsevier
Acid-sensing ion channel 1a (ASIC1a) is a proton-gated channel involved in synaptic
transmission, pain signalling, and several ischemia-associated pathological conditions. The …

Pathology and Physiology of Acid-Sensitive Ion Channels in the Bladder

Y Zhang, D Dong, J Zhang, F Zhen, M Li, B Chen - Heliyon, 2024 - cell.com
Acid-sensitive ion channels (ASICs) are sodium-permeable channels activated by
extracellular acidification. They can be activated and trigger the inward flow of Na+ when the …

ASIC3-activated key enzymes of de novo lipid synthesis supports lactate-driven EMT and the metastasis of colorectal cancer cells

X Wan, F Li, Z Li, L Zhou - Cell Communication and Signaling, 2024 - Springer
Acidic microenvironments is a cancer progression driver, unclear core mechanism hinders
the discovery of new diagnostic or therapeutic targets. ASIC3 is an extracellular proton …

Mutagenesis of the Peptide Inhibitor of ASIC3 Channel Introduces Binding to Thumb Domain of ASIC1a but Reduces Analgesic Activity

TA Khasanov, EE Maleeva, SG Koshelev, VA Palikov… - Marine Drugs, 2024 - mdpi.com
Acid-sensing ion channels (ASICs), which act as proton-gating sodium channels, have
garnered attention as pharmacological targets. ASIC1a isoform, notably prevalent in the …

[PDF][PDF] КЛІНІЧНІ ТА БІОХІМІЧНІ МАРКЕРИ ВЕРТЕБРОГЕННИХ ПОПЕРЕКОВО-КРИЖОВИХ БОЛЬОВИХ СИНДРОМІВ

АР КУЛИК - library.dmed.org.ua
Дисертація на здобуття ступеня доктора філософії в галузі знань 22 Охорона здоров'я
за спеціальністю 222 Медицина.–Львівський національний медичний університет імені …