Immune dysfunction in aged horses

D McFarlane - Veterinary Clinics: Equine Practice, 2016 - vetequine.theclinics.com
Immunosenescence is the term that describes age-associated remodeling of the immune
system that occurs in the elderly, resulting in poor immunity and an exaggerated …

Report from the second cytomegalovirus and immunosenescence workshop

M Wills, A Akbar, M Beswick, JA Bosch, C Caruso… - Immunity & …, 2011 - Springer
Abstract The Second International Workshop on CMV & Immunosenescence was held in
Cambridge, UK, 2-4 th December, 2010. The presentations covered four separate sessions …

IFNγ TNFα IL2 MIP1α CD107a + PRF1 + CD8 pp65-Specific T-Cell …

S Ferrando-Martínez, E Ruiz-Mateos… - … Series A: Biomedical …, 2015 - academic.oup.com
Persistent cytomegalovirus (CMV) infection has been suggested to be a major driving force
in the immune deterioration and an underlying source of age-related diseases in the elderly …

Yin and yang of immunological memory in controlling infections: Overriding self defence mechanisms

RK Roy, R Yadav, A Jain, V Tripathi… - International Reviews …, 2022 - Taylor & Francis
Immunological memory is critical for host immunity and decisive for individual to respond
exponentially to previously encountered infection. Both T and B cell memory are known to …

T and B Cell Metabolism in Older Adults

Y Zhang, HCJ Ertl - Immunometabolism, 2020 - journals.lww.com
Immunosenescence, a process that describes age-related declines in immune responses,
renders the elderly more susceptible to infections and malignancies. Many changes that …

Flow cytometric characterization of antigen-specific T cells based on RNA and its advantages in detecting infections and immunological disorders

F Radford, S Tyagi, ML Gennaro… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Fluorescence in situ hybridization coupled with flow cytometry (FISH-Flow) is a highly
quantitative, high-throughput platform allowing precise quantification of total mRNA …

Analisi della replicazione virale di Citomegalovirus e del virus di Epstein-Barr su sangue periferico in una coorte di pazienti affetti da Immunodeficienza Comune …

L Marri - 2023 - unire.unige.it
Background: While Common variable immunodeficiency (CVID) is characterized by
hypogammaglobulinemia and failure of specific antibody production due to B-cell defects …

Geriatria equina: revisão de literatura

LA Diniz - 2022 - repositorio.ufmg.br
A medicina geriátrica está relacionada ao estudo de patologias comuns em pacientes
idosos e o entendimento de como estas doenças diferem suas apresentações na velhice. O …

In silico and in vitro arboviral MHC class I-restricted-epitope signatures reveal immunodominance and poor overlapping patterns

ÁL Ribeiro, FP Araujo, PM Oliveira, LA Teixeira… - 2022 - arca.fiocruz.br
Introduction: The present work sought to identify MHC-I-restricted peptide signatures for
arbovirus using in silico and in vitro peptide microarray tools. Methods: First, an in-silico …

老年人免疫特征与过敏性鼻炎

张琳, 刘莹, 程雷 - 中华临床免疫和变态反应杂志, 2014 - cqvip.com
老年人免疫功能随年龄增长出现减退, 最突出的表现是T 细胞功能下降. 过敏性鼻炎在老年人群
中的发生率相对较低, 这可能与机体免疫应答随衰老而减弱有关. 研究表明 …