Advances and highlights in biomarkers of allergic diseases

I Ogulur, Y Pat, O Ardicli, E Barletta, L Cevhertas… - Allergy, 2021 - Wiley Online Library
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …

Advances and highlights in asthma in 2021

I Agache, I Eguiluz‐Gracia, C Cojanu, A Laculiceanu… - Allergy, 2021 - Wiley Online Library
Last year brought a significant advance in asthma management, unyielding to the pressure
of the pandemics. Novel key findings in asthma pathogenesis focus on the resident cell …

[HTML][HTML] Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial

SG Kelsen, IO Agache, W Soong, E Israel… - Journal of allergy and …, 2021 - Elsevier
Background The IL-33/ST2 pathway is linked with asthma susceptibility. Inhaled allergens,
pollutants, and respiratory viruses, which trigger asthma exacerbations, induce release of IL …

[PDF][PDF] EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023

WJ Fokkens, AS Viskens, V Backer, D Conti… - Rhinology, 2023 - sioechcf.it
Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a
significant impact on the quality of life (QoL). It is typically characterized by a type 2 …

Advances and recent developments in asthma in 2020

L Cevhertas, I Ogulur, DJ Maurer, D Burla, M Ding… - Allergy, 2020 - Wiley Online Library
In this review, we discuss recent publications on asthma and review the studies that have
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: analysis of the REDES study

I Pavord, F Gardiner, LG Heaney, C Domingo… - Frontiers in …, 2023 - frontiersin.org
Introduction Clinical remission as a multicomponent treatment goal in severe asthma is
being explored in clinical practice. This post hoc analysis used data from the REDES study …

Type 2 chronic inflammatory diseases: targets, therapies and unmet needs

P Kolkhir, CA Akdis, M Akdis, C Bachert… - Nature Reviews Drug …, 2023 - nature.com
Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …

[HTML][HTML] Chronic rhinosinusitis with nasal polyps: quality of life in the biologics era

J Mullol, A Azar, KM Buchheit, C Hopkins… - The Journal of Allergy …, 2022 - Elsevier
Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …