Piezo1 regulates calcium oscillations and cytokine release from astrocytes

M Velasco‐Estevez, SO Rolle, M Mampay, KK Dev… - Glia, 2020 - Wiley Online Library
Astrocytes are important for information processing in the brain and they achieve this by fine‐
tuning neuronal communication via continuous uptake and release of biochemical …

[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy

S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Astrocytes in the regulation of cerebrovascular functions

M Cohen‐Salmon, L Slaoui, N Mazaré, A Gilbert… - Glia, 2021 - Wiley Online Library
Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …

Astrocytes in multiple sclerosis

SK Ludwin, VTS Rao, CS Moore… - Multiple sclerosis …, 2016 - journals.sagepub.com
Recent experimental and clinical studies on astrocytes are unraveling the capabilities of
these multi-functional cells in normal homeostasis, and in central nervous system (CNS) …

[HTML][HTML] Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

CK Prajeeth, J Kronisch, R Khorooshi, B Knier… - Journal of …, 2017 - Springer
Abstract Background Autoreactive Th1 and Th17 cells are believed to mediate the pathology
of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia …

[HTML][HTML] Histamine, neuroinflammation and neurodevelopment: a review

E Carthy, T Ellender - Frontiers in neuroscience, 2021 - frontiersin.org
The biogenic amine, histamine, has been shown to critically modulate inflammatory
processes as well as the properties of neurons and synapses in the brain, and is also …

Achievements and obstacles of remyelinating therapies in multiple sclerosis

M Stangel, T Kuhlmann, PM Matthews… - Nature Reviews …, 2017 - nature.com
Remyelination in the CNS is the natural process of damage repair in demyelinating
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …

[HTML][HTML] Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy

J Loos, S Schmaul, TM Noll, M Paterka… - Journal of …, 2020 - Springer
Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context
of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 …

[HTML][HTML] Glial cell response to Epstein-Barr Virus infection: A plausible contribution to virus-associated inflammatory reactions in the brain

S Jakhmola, HC Jha - Virology, 2021 - Elsevier
Abstract Epstein-Barr Virus (EBV) is clinically related to various neurological ailments. The
manipulation of neural homeostasis through altered glial cells functions is enigmatic. We …

[HTML][HTML] A microengineered Brain-Chip to model neuroinflammation in humans

I Pediaditakis, KR Kodella, DV Manatakis, CY Le… - Iscience, 2022 - cell.com
Species differences in brain and blood–brain barrier (BBB) biology hamper the translation of
findings from animal models to humans, impeding the development of therapeutics for brain …