Background Central nervous system (CNS) astrocytes have various functions in the central
nervous system (CNS). Many neurodegenerative diseases are associated with astrocyte …

Adenine nucleotides (AdNs) play important roles in immunity and inflammation. Extracellular
AdNs, such as adenosine triphosphate (ATP) or nicotinamide adenine dinucleotide (NAD) …

Along the last years it has been demonstrated that non-neural cells play a major role in the
pathogenesis of the primary degenerative disorders (PDDs) of the human central nervous …

Nucleotide-binding, leucine-rich repeat containing X1 (NLRX1) is a mitochondria-located
innate immune sensor that inhibits major pro-inflammatory pathways such as type I …

Gap junctions (GJs) coupling oligodendrocytes to astrocytes and to other oligodendrocytes
are formed mainly by connexin47 (Cx47) and a smaller portion by connexin32 (Cx32) …

Multiple sclerosis (MS) is an autoimmune demyelinating disease affecting the central
nervous system (CNS). T helper (Th) 17 cells are involved in the pathogenesis of MS and its …

This review demonstrates the importance of uncovering the mechanisms that underlie
chemotherapy-induced neuroinflammation. It builds upon the well-established connection …

Currently, there is no definitive cure for epilepsy. The available medications relieve
symptoms and reduce seizure attacks. The major challenge with the available antiepileptic …

Exposure to atmospheric particulate matter (PM) has been found to accelerate the onset of
neurological disorders via the induction of detrimental neuroinflammatory responses. To …

Epilepsy and multiple sclerosis (MS), two of the most common neurological diseases, are
characterized by the establishment of inflammatory environment in the central nervous …