Conditioning intensity and peritransplant flow cytometric MRD dynamics in adult AML
G Paras, LM Morsink, M Othus, F Milano… - Blood, The Journal …, 2022 - ashpublications.org
In acute myeloid leukemia (AML), measurable residual disease (MRD) before or after
allogeneic hematopoietic cell transplantation (HCT) is an established independent indicator …
allogeneic hematopoietic cell transplantation (HCT) is an established independent indicator …
Initial diagnostic workup of acute leukemia: guideline from the College of American Pathologists and the American Society of Hematology
DA Arber, MJ Borowitz, M Cessna… - … of pathology & …, 2017 - meridian.allenpress.com
Context.—A complete diagnosis of acute leukemia requires knowledge of clinical
information combined with morphologic evaluation, immunophenotyping and karyotype …
information combined with morphologic evaluation, immunophenotyping and karyotype …
The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML
N Shayegi, M Kramer, M Bornhäuser… - Blood, The Journal …, 2013 - ashpublications.org
Mutations of the NPM1 gene (NPM1 mut) are among the most common genetic alterations in
acute myeloid leukemia and are suitable for minimal residual disease detection. We …
acute myeloid leukemia and are suitable for minimal residual disease detection. We …
Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
Relapsed or refractory pediatric acute myeloid leukemia (AML) is associated with poor
outcomes and relapse risk prediction approaches have not changed significantly in …
outcomes and relapse risk prediction approaches have not changed significantly in …
Measurable residual disease, conditioning regimen intensity, and age predict outcome of allogeneic hematopoietic cell transplantation for acute myeloid leukemia in …
MH Gilleece, M Labopin, I Yakoub‐Agha… - American journal of …, 2018 - Wiley Online Library
Patients with acute myeloid leukemia (AML) in morphological first complete remission (CR1)
pre‐allogeneic hematopoietic cell transplantation (HCT) may have measurable residual …
pre‐allogeneic hematopoietic cell transplantation (HCT) may have measurable residual …
CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia
MA Biernacki, KA Foster, KB Woodward… - The Journal of …, 2020 - Am Soc Clin Investig
Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute
myeloid leukemia (AML), often necessary for leukemogenesis, persistent throughout the …
myeloid leukemia (AML), often necessary for leukemogenesis, persistent throughout the …
Secondary genetic lesions in acute myeloid leukemia with inv (16) or t (16; 16): a study of the German-Austrian AML Study Group (AMLSG)
P Paschka, J Du, RF Schlenk, VI Gaidzik… - Blood, The Journal …, 2013 - ashpublications.org
In this study, we evaluated the impact of secondary genetic lesions in acute myeloid
leukemia (AML) with inv (16)(p13. 1q22) or t (16; 16)(p13. 1; q22); CBFB-MYH11. We …
leukemia (AML) with inv (16)(p13. 1q22) or t (16; 16)(p13. 1; q22); CBFB-MYH11. We …
Advances in acute myeloid leukemia: recently approved therapies and drugs in development
Simple Summary Acute myeloid leukemia (AML) is one of the most common types of
leukemia in adults, with an average first diagnosis at age 68, and has historically carried …
leukemia in adults, with an average first diagnosis at age 68, and has historically carried …
CD36 drives metastasis and relapse in acute myeloid leukemia
Identifying mechanisms underlying relapse is a major clinical issue for effective cancer
treatment. The emerging understanding of the importance of metastasis in hematologic …
treatment. The emerging understanding of the importance of metastasis in hematologic …
Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center
RB Walter, M Othus, AK Burnett, B Löwenberg… - Leukemia, 2015 - nature.com
Therapeutic resistance remains the principal problem in acute myeloid leukemia (AML). We
used area under receiver-operating characteristic curves (AUCs) to quantify our ability to …
used area under receiver-operating characteristic curves (AUCs) to quantify our ability to …