A comprehensive review of natural product-derived compounds acting on P2× 7R: the promising therapeutic drugs in disorders

Z Liu, W Liu, M Han, M Wang, Y Li, Y Yao, Y Duan - Phytomedicine, 2023 - Elsevier
Abstract Background The P2× 7 receptor (P2× 7R) is known to play a significant role in
regulating various pathological processes associated with immune regulation …

Sennoside A restrains TRAF6 level to modulate ferroptosis, inflammation and cognitive impairment in aging mice with Alzheimer's Disease

X Li, X Wang, B Huang, R Huang - International immunopharmacology, 2023 - Elsevier
Background Alzheimer's disease (AD) is a common neurodegenerative disease and a
momentous cause of dementia in the elderly. Sennoside A (SA) is an anthraquinone …

Structural Characterization and Anticancer Activity of a New Anthraquinone from Senna velutina (Fabaceae)

DTH Castro, DF Leite, D da Silva Baldivia… - Pharmaceuticals, 2023 - mdpi.com
In this study, a novel compound was isolated, identified, and its chemical structure was
determined from the extract of the roots of Senna velutina. In addition, we sought to evaluate …

Plant Secondary Metabolites of the Genus Senna. Biological Properties in the Context of Medical Research

P Sitarek, J Sikora, M Dudzic, D Boczkowski… - Plant Specialized …, 2023 - Springer
The genus Senna is a member of the legume family (Fabaceae) and has about 300 species
that are widespread in tropical and subtropical regions of Africa, Asia, Europe, and Latin …

Structural Characterization and Anticancer Activity of a New Anthraquinone from Senna velutina

DTH Castro, DF Leite, D da Silva Baldívia… - 2023 - preprints.org
Cancer is a complex disease, considered a major public health problem worldwide. Among
the types of cancer, melanoma, and leukemias present high mortality rates in Brazil and …