We studied the alterations in myocardial beta-adrenergic receptor-adenylate cyclase activity
and muscarinic receptor density in a canine model of left ventricular (LV) failure. LV failure …

A sensitive, specific and selective method has been developed for the simultaneous
determination of bisoprolol and hydrochlorothiazide in human plasma. The method …

The aim of this study was to compare the effects of long-term monotherapy with four different
β-blockers on plasma lipids in hypercholesterolemic hypertensive patients. We studied 152 …

Synopsis Bisoprolol is a β: 1-adrenoceptor antagonist with no partial agonist (intrinsic
sympathomimetic) activity or membrane stabilising (local anaesthetic) activity. The oral …

Rhubarbs and their extractives have been used as cathartic for many years. There have
been numerous breakthroughs in the pharmacological research of the drug. However, as …

The blocking and stimulant potencies of (−)-pindolol and (+)-pindolol were estimated on
right atria and tracheae of guinea pig. Blocking affinities were estimated for β-adrenoceptor …

The pharmacodynamic profile of bisoprolol, a new beta 1‐selective adrenoceptor
antagonist, was investigated in four independent studies including 36 healthy male …

On the isolated electrically driven muscle strip of human right atrial appendages the β-
adrenoceptor subtypes mediating the positive inotropic effects of isoprenaline, dobutamine …

Carvedilol is reported to prevent cancers in humans and animal models. However, a
molecular mechanism has yet to be established, and the extent to which other β-blockers …

Bisoprolola β1-selective β-blockerwas administered to 13 patients with mild to moderate
essential hypertension once daily at doses of 5–10 mg for 24 weeksand its long-term effects …