Idiopathic pulmonary fibrosis: an update on pathogenesis
Q Mei, Z Liu, H Zuo, Z Yang, J Qu - Frontiers in pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
Idiopathic pulmonary fibrosis: Current and future treatment
DS Glass, D Grossfeld, HA Renna… - The clinical …, 2022 - Wiley Online Library
Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …
Idiopathic pulmonary fibrosis (an update) and progressive pulmonary fibrosis in adults: an official ATS/ERS/JRS/ALAT clinical practice guideline
G Raghu, M Remy-Jardin, L Richeldi… - American Journal of …, 2022 - atsjournals.org
Background: This American Thoracic Society, European Respiratory Society, Japanese
Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior …
Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior …
Targeting galectin-driven regulatory circuits in cancer and fibrosis
Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …
broad range of physiological and pathological processes. As a group, these proteins use …
Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
Precise identification of cell states altered in disease using healthy single-cell references
Joint analysis of single-cell genomics data from diseased tissues and a healthy reference
can reveal altered cell states. We investigate whether integrated collections of data from …
can reveal altered cell states. We investigate whether integrated collections of data from …
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling
J Liu, Z Wu, Y Liu, Z Zhan, L Yang, C Wang… - Journal of …, 2022 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …
TGF‑β1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis
Z Ye, Y Hu - International journal of molecular …, 2021 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is a worldwide disease characterized by the chronic and
irreversible decline of lung function. Currently, there is no drug to successfully treat the …
irreversible decline of lung function. Currently, there is no drug to successfully treat the …
Integrins as a drug target in liver fibrosis
As the worldwide prevalence of chronic liver diseases is high and continuing to increase,
there is an urgent need for treatment to prevent cirrhosis‐related morbidity and mortality …
there is an urgent need for treatment to prevent cirrhosis‐related morbidity and mortality …
Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Fibrotic diseases cause organ failure that lead to~ 45% of all deaths in the United States.
Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to …
Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to …