[HTML][HTML] Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy

Q Yang, B Wang, Q Zheng, H Li, X Meng… - Advanced …, 2023 - Wiley Online Library
Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer
progression, primarily by remodeling the tumor microenvironment and regulating key …

The gut microbiota in breast cancer development and treatment: The good, the bad, and the useful!

D Nandi, S Parida, D Sharma - Gut Microbes, 2023 - Taylor & Francis
Regardless of the global progress in early diagnosis and novel therapeutic regimens, breast
carcinoma poses a devastating threat, and the advances are somewhat marred by high …

Microbial endocrinology: the mechanisms by which the microbiota influences host sex steroids

S Cotton, CA Clayton, C Tropini - Trends in Microbiology, 2023 - cell.com
Recent progress in microbial endocrinology has propelled this field from initially providing
correlational links to defining the mechanisms by which microbes influence systemic sex …

[HTML][HTML] Exploring the potential impact of probiotic use on drug metabolism and efficacy

C Purdel, A Ungurianu, I Adam-Dima… - Biomedicine & …, 2023 - Elsevier
Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …

Role of the microbiome in oral cancer occurrence, progression and therapy

Z Li, Y Liu, L Zhang - Microbial Pathogenesis, 2022 - Elsevier
The oral cavity, like other digestive or mucosal sites, contains a site-specific microbiome that
plays a significant role in maintaining health and homeostasis. Strictly speaking, the …

An Organ‐on‐Chip Platform for Simulating Drug Metabolism Along the Gut–Liver Axis

M Lucchetti, KO Aina, L Grandmougin… - Advanced …, 2024 - Wiley Online Library
The human microbiome significantly influences drug metabolism through the gut–liver axis,
leading to modified drug responses and potential toxicity. Due to the complex nature of the …

[HTML][HTML] Pharmacomicrobiomics in anticancer therapies: why the gut microbiota should be pointed out

G Conti, F D'Amico, M Fabbrini, P Brigidi, M Barone… - Genes, 2022 - mdpi.com
Anticancer treatments have shown a variable therapeutic outcome that may be partly
attributable to the activity of the gut microbiota on the pathology and/or therapies. In recent …

[HTML][HTML] Decreased tissue omega-6/omega-3 fatty acid ratio prevents chemotherapy-induced gastrointestinal toxicity associated with alterations of gut microbiome

K Kaliannan, SO Donnell, K Murphy, C Stanton… - International Journal of …, 2022 - mdpi.com
Gastrointestinal toxicity (GIT) is a debilitating side effect of Irinotecan (CPT-11) and limits its
clinical utility. Gut dysbiosis has been shown to mediate this side effect of CPT-11 by …

[HTML][HTML] Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in …

J He, S Han, Y Wang, Q Kang, X Wang, Y Su… - Biomedicine & …, 2023 - Elsevier
Chemotherapy leads to significant side effects in patients, especially in the gut, resulting in
various clinical manifestations and enhanced economic pressure. Until now, many of the …