[HTML][HTML] Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications
LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …
accumulating evidence has clarified the complex role of the human microbiota in the …
A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy
Q Yang, B Wang, Q Zheng, H Li, X Meng… - Advanced …, 2023 - Wiley Online Library
Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer
progression, primarily by remodeling the tumor microenvironment and regulating key …
progression, primarily by remodeling the tumor microenvironment and regulating key …
The gut microbiota in breast cancer development and treatment: The good, the bad, and the useful!
Regardless of the global progress in early diagnosis and novel therapeutic regimens, breast
carcinoma poses a devastating threat, and the advances are somewhat marred by high …
carcinoma poses a devastating threat, and the advances are somewhat marred by high …
Microbial endocrinology: the mechanisms by which the microbiota influences host sex steroids
S Cotton, CA Clayton, C Tropini - Trends in Microbiology, 2023 - cell.com
Recent progress in microbial endocrinology has propelled this field from initially providing
correlational links to defining the mechanisms by which microbes influence systemic sex …
correlational links to defining the mechanisms by which microbes influence systemic sex …
[HTML][HTML] Exploring the potential impact of probiotic use on drug metabolism and efficacy
Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …
supplements, but are also recommended in treating or preventing various gastrointestinal …
Role of the microbiome in oral cancer occurrence, progression and therapy
Z Li, Y Liu, L Zhang - Microbial Pathogenesis, 2022 - Elsevier
The oral cavity, like other digestive or mucosal sites, contains a site-specific microbiome that
plays a significant role in maintaining health and homeostasis. Strictly speaking, the …
plays a significant role in maintaining health and homeostasis. Strictly speaking, the …
An Organ‐on‐Chip Platform for Simulating Drug Metabolism Along the Gut–Liver Axis
M Lucchetti, KO Aina, L Grandmougin… - Advanced …, 2024 - Wiley Online Library
The human microbiome significantly influences drug metabolism through the gut–liver axis,
leading to modified drug responses and potential toxicity. Due to the complex nature of the …
leading to modified drug responses and potential toxicity. Due to the complex nature of the …
[HTML][HTML] Pharmacomicrobiomics in anticancer therapies: why the gut microbiota should be pointed out
Anticancer treatments have shown a variable therapeutic outcome that may be partly
attributable to the activity of the gut microbiota on the pathology and/or therapies. In recent …
attributable to the activity of the gut microbiota on the pathology and/or therapies. In recent …
[HTML][HTML] Decreased tissue omega-6/omega-3 fatty acid ratio prevents chemotherapy-induced gastrointestinal toxicity associated with alterations of gut microbiome
K Kaliannan, SO Donnell, K Murphy, C Stanton… - International Journal of …, 2022 - mdpi.com
Gastrointestinal toxicity (GIT) is a debilitating side effect of Irinotecan (CPT-11) and limits its
clinical utility. Gut dysbiosis has been shown to mediate this side effect of CPT-11 by …
clinical utility. Gut dysbiosis has been shown to mediate this side effect of CPT-11 by …
[HTML][HTML] Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in …
J He, S Han, Y Wang, Q Kang, X Wang, Y Su… - Biomedicine & …, 2023 - Elsevier
Chemotherapy leads to significant side effects in patients, especially in the gut, resulting in
various clinical manifestations and enhanced economic pressure. Until now, many of the …
various clinical manifestations and enhanced economic pressure. Until now, many of the …