Gastrointestinal involvement in Parkinson's disease: pathophysiology, diagnosis, and management

T Warnecke, KH Schäfer, I Claus, K Del Tredici… - npj Parkinson's …, 2022 - nature.com
Growing evidence suggests an increasing significance for the extent of gastrointestinal tract
(GIT) dysfunction in Parkinson's disease (PD). Most patients suffer from GIT symptoms …

Gastrointestinal dysfunction in Parkinson's disease

A Fasano, NP Visanji, LWC Liu, AE Lang… - The Lancet …, 2015 - thelancet.com
Our understanding of dysfunction of the gastrointestinal system in patients with Parkinson's
disease has increased substantially in the past decade. The entire gastrointestinal tract is …

Dysphagia in Parkinson's disease

I Suttrup, T Warnecke - Dysphagia, 2016 - Springer
More than 80% of patients with Parkinson's disease (PD) develop dysphagia during the
course of their disease. Swallowing impairment reduces quality of life, complicates …

[HTML][HTML] Arizona study of aging and neurodegenerative disorders and brain and body donation program

TG Beach, CH Adler, LI Sue, G Serrano… - … : official journal of the …, 2015 - ncbi.nlm.nih.gov
Abstract The Brain and Body Donation Program (BBDP) at Banner Sun Health Research
Institute (http://www. brainandbodydonationprogram. org) started in 1987 with brain-only …

Neuropathological basis of nonmotor manifestations of Parkinson's disease

CH Adler, TG Beach - Movement Disorders, 2016 - Wiley Online Library
Nonmotor manifestations of Parkinson's disease (PD) can begin well before motor PD
begins. It is now clear, from clinical and autopsy studies, that there is significant Lewy‐type α …

Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches

K Dashtipour, A Tafreshi, J Lee… - Neurodegenerative …, 2018 - Taylor & Francis
The prevalence of speech disorders among individuals with Parkinson's disease (PD) has
been reported to be as high as 89%. Speech impairment in PD results from a combination of …

Critical dysphagia is common in Parkinson disease and occurs even in early stages: a prospective cohort study

C Pflug, M Bihler, K Emich, A Niessen, JC Nienstedt… - Dysphagia, 2018 - Springer
To assess the prevalence of dysphagia and its typical findings in unselected “real-world”
Parkinson patients using an objective gold-standard method. This was a prospective …

Management of dysphagia in patients with Parkinson's disease and related disorders

G Umemoto, H Furuya - Internal Medicine, 2020 - jstage.jst.go.jp
Various methods of rehabilitation for dysphagia have been suggested through the
experience of treating stroke patients. Although most of these patients recover their …

Gastrointestinal dysfunction in Parkinson's disease

C Skjærbæk, K Knudsen, J Horsager… - Journal of Clinical …, 2021 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease. Patients
show deposits of pathological, aggregated α-synuclein not only in the brain but throughout …

Parkinson disease affects peripheral sensory nerves in the pharynx

L Mu, S Sobotka, J Chen, H Su… - … of Neuropathology & …, 2013 - academic.oup.com
Dysphagia is very common in patients with Parkinson disease (PD) and often leads to
aspiration pneumonia, the most common cause of death in PD. Current therapies are largely …