Glucose-induced insulin secretion in response to a step increase in blood glucose
concentrations follows a biphasic time course consisting of a rapid and transient first phase …

Over the last years, the metabolic role of PRL has emerged. PRL excess is known to
promote weight gain, obesity, metabolic syndrome, and impairment in gluco-insulinemic and …

Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central
nervous system that also act in the pancreas as peripheral regulators of metabolism …

Dopamine signaling is mediated by five cloned receptors, grouped into D1-like (D1 and D5)
and D2-like (D2, D3 and D4) families. We identified by reverse transcription-PCR the …

Hyperinsulinism is the single most common mechanism of hypoglycemia in neonates.
Dysregulated insulin secretion is responsible for the transient and prolonged forms of …

The relationship between antidopaminergic drugs and glucose has not been extensively
studied, even though chronic neuroleptic treatment causes hyperinsulinemia in normal …

Background: Hypoglycemia in infants and children can lead to seizures, developmental
delay, and permanent brain damage. Hyperinsulinism (HI) is the most common cause of …

Although long-studied in the central nervous system, there is increasing evidence that
dopamine (DA) has important roles in the periphery including in metabolic regulation. Insulin …

The importance of dopamine in central nervous system function is well known, but its effects
on glucose homeostasis and pancreatic β cell function are beginning to be unraveled …

In the early sixties, a discussion started regarding the association between Parkinson's
disease (PD) and type II diabetes mellitus (T2DM). Today, this potential relationship is still a …