[HTML][HTML] New strategies and perspectives on managing IgA nephropathy
H Selvaskandan, CK Cheung, M Muto… - Clinical and experimental …, 2019 - Springer
IgA nephropathy is an inflammatory renal disease characterised by the deposition of IgA in
the glomerular mesangium and is the most commonly reported primary glomerulonephritis …
the glomerular mesangium and is the most commonly reported primary glomerulonephritis …
[HTML][HTML] Perspectives on how mucosal immune responses, infections and gut microbiome shape IgA nephropathy and future therapies
Infections have been considered to play a critical role in the pathogenesis of IgA
nephropathy (IgAN) because synpharyngitic hematuria is a common feature in IgAN …
nephropathy (IgAN) because synpharyngitic hematuria is a common feature in IgAN …
IgA vasculitis with nephritis: update of pathogenesis with clinical implications
IgA vasculitis with nephritis (IgAVN) shares many pathogenetic features with IgA
nephropathy (IgAN). The purpose of this review is to describe our current understanding of …
nephropathy (IgAN). The purpose of this review is to describe our current understanding of …
[HTML][HTML] The contribution of complement to the pathogenesis of IgA nephropathy: are complement-targeted therapies moving from rare disorders to more common …
F Poppelaars, B Faria, W Schwaeble… - Journal of clinical …, 2021 - mdpi.com
Primary IgA nephropathy (IgAN) is a leading cause of chronic kidney disease and kidney
failure for which there is no disease-specific treatment. However, this could change, since …
failure for which there is no disease-specific treatment. However, this could change, since …
[HTML][HTML] Aberrantly glycosylated IgA1 in IgA nephropathy: What we know and what we don't know
Y Ohyama, MB Renfrow, J Novak… - Journal of Clinical …, 2021 - mdpi.com
IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is
characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 …
characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 …
Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link
H Selvaskandan, J Barratt… - International Journal of …, 2022 - Wiley Online Library
IgA nephropathy (IgAN) is the most common pattern of primary glomerular disease reported
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …
[HTML][HTML] IgA vasculitis and IgA nephropathy: same disease?
E Pillebout - Journal of clinical medicine, 2021 - mdpi.com
Many authors suggested that IgA Vasculitis (IgAV) and IgA Nephropathy (IgAN) would be
two clinical manifestations of the same disease; in particular, that IgAV would be the …
two clinical manifestations of the same disease; in particular, that IgAV would be the …
Markers for the progression of IgA nephropathy
D Maixnerova, C Reily, Q Bian, M Neprasova… - Journal of …, 2016 - Springer
We have summarized the latest findings on markers for progression of immunoglobulin A
(IgA) nephropathy (IgAN), the most common primary glomerulonephritis with a high …
(IgA) nephropathy (IgAN), the most common primary glomerulonephritis with a high …
Targeting complement in IgA nephropathy
F Caravaca-Fontán, E Gutiérrez… - Clinical Kidney …, 2023 - academic.oup.com
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. Recent years have witnessed significant improvements in the understanding of …
worldwide. Recent years have witnessed significant improvements in the understanding of …
[HTML][HTML] Be on target: strategies of targeting alternative and lectin pathway components in complement-mediated diseases
The complement system has moved into the focus of drug development efforts in the last
decade, since its inappropriate or uncontrolled activation has been recognized in many …
decade, since its inappropriate or uncontrolled activation has been recognized in many …