Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors

F Askarian, T Wagner, M Johannessen… - FEMS microbiology …, 2018 - academic.oup.com
Early recognition of pathogens by the innate immune system is crucial for bacterial
clearance. Many pattern recognition receptors (PRRs) such as Toll-like (TLRs) and (NOD) …

[HTML][HTML] Intrinsic and extrinsic regulation of innate immune receptors

E Jeong, JY Lee - Yonsei medical journal, 2011 - ncbi.nlm.nih.gov
Pattern recognition receptors (PRRs) in innate immune cells play a pivotal role in the first
line of host defense system. PRRs recognize pathogen-associated molecular patterns …

Regulation of intestinal inflammation by soybean and soy-derived compounds

AR Basson, S Ahmed, R Almutairi, B Seo, F Cominelli - Foods, 2021 - mdpi.com
Environmental factors, particularly diet, are considered central to the pathogenesis of the
inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. In particular, the …

Modulation of γδ T cell responses by TLR ligands

D Wesch, C Peters, HH Oberg, K Pietschmann… - Cellular and molecular …, 2011 - Springer
Toll-like receptors (TLR) are pattern-recognition receptors that recognize a broad variety of
structurally conserved molecules derived from microbes. The recognition of TLR ligands …

Toll-like receptors: promising therapeutic targets for inflammatory diseases

A Achek, D Yesudhas, S Choi - Archives of pharmacal research, 2016 - Springer
The health of living organisms is constantly challenged by bacterial and viral threats. The
recognition of pathogenic microorganisms by diverse receptors triggers a variety of host …

Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor …

MI Kurki, SK Häkkinen, J Frösen, R Tulamo… - …, 2011 - journals.lww.com
BACKGROUND: Aneurysmal subarachnoid hemorrhage, almost always from saccular
intracranial aneurysm (sIA), is a devastating form of stroke that affects the working-age …

Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence

S González-Reyes, JM Fernández… - Cancer immunology …, 2011 - Springer
Abstract Background Toll-like receptors (TLRs) have garnered an extraordinary amount of
interest in cancer research due to their role in tumor progression. By activating the …

[HTML][HTML] Toll-like receptors and prostate cancer

S Zhao, Y Zhang, Q Zhang, F Wang… - Frontiers in …, 2014 - frontiersin.org
Prostate cancer is the second leading cause of cancer-related death in men after lung
cancer. Immune responses clearly play a critical role in the tumorigenesis and in the efficacy …

Polyhydroxylated Metallofullerenols Stimulate IL‐1β Secretion of Macrophage through TLRs/MyD88/NF‐κB Pathway and NLRP3 Inflammasome Activation

Z Chen, Y Liu, B Sun, H Li, J Dong, L Zhang, L Wang… - Small, 2014 - Wiley Online Library
A number of functionalized fullerene derivatives have been widely investigated in biological
applications after the main problem of poor solubility in the cellular environment was solved …

RNA‐Based Immunostimulatory Liposomal Spherical Nucleic Acids as Potent TLR7/8 Modulators

C Guan, N Chernyak, D Dominguez, L Cole, B Zhang… - Small, 2018 - Wiley Online Library
Immunostimulatory spherical nucleic acids (IS‐LSNAs) comprised of RNA selective for toll‐
like receptors (TLRs) 7/8 are synthesized and characterized. These structures consist of …