Reduced infarct volume in TLR2-knockout mice compared with C57Bl/6 wild-type mice has
recently been shown in experimental stroke and confirmed in this study. We now also show …

Recognition of the pathogen-associated molecular pattern (PAMP) by host Toll-like
receptors (TLR) is an important component of the innate immune response for countering …

Aim We demonstrate the effect of PDE5 inhibitors in cases of acute lung injury via the
relationship between cGMP/NO and the TLR4-NF-κB-NLRP3 pathway. Materials and …

Abstract Context Kaihoujian Throat Spray children's type (KHJSC) is a Chinese medicine
prescription for treating pediatric acute pharyngitis and tonsillitis (APT). However, its relevant …

Toll-like receptors (TLR) are important innate immune proteins for the identification and
clearance of invading pathogen. TLR signal through adaptor proteins, most commonly …

Extracellular matrix (ECM) components, commonly thought to function purely as structural
elements are now demonstrated to act as signaling molecules. With the identification of …

Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like
receptor ligands - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Background Balanced activation and inhibition of the immune system ensures pathogen
clearance while avoiding hyperinflammation. Siglecs, sialic acid–binding proteins found on …

Toll‐like receptors are important pattern recognition receptors which have key roles in both
innate and adaptive immune responses. They are strongly associated with the pathogenesis …

Cardiolipins (CLs) are tetra-acylated diphosphatidylglycerols found in bacteria, yeast, plants,
and animals. In healthy mammals, CLs are unsaturated, whereas saturated CLs are found in …