Chemokines constitute a family of chemoattractant cytokines and are subdivided into four
families on the basis of the number and spacing of the conserved cysteine residues in the N …

Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …

Over the past ten years, numerous chemokines have been identified as attractants of
different types of blood leukocytes to sites of infection and inflammation. They are produced …

The burgeoning field of leukocyte trafficking has created new and exciting opportunities in
the clinic. Trafficking signals are being defined that finely control the movement of distinct …

We examine here several diseases that are associated with inappropriate activation of the
chemokine network. Detailed comment has been restricted to pathological states for which …

Chemokines and their receptors are involved in the pathogenesis of diseases ranging from
asthma to AIDS. Chemokine receptors are G-protein-coupled serpentine receptors that …

Chemokines are a family of low molecular weight proteins with an essential role in leukocyte
trafficking during both homeostasis and inflammation. The CC class of chemokines consists …

Chemokines are the largest family of cytokines in human immunophysiology. These proteins
are defined by four invariant cysteines and are categorized based on the sequence around …

Baggiolini M (Theodor Kocher Institute, University of Bern, and Institute for Research in
Biomedicine, Bellinzona, Switzerland). Chemokines in pathology and medicine (Review). J …