Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in
the joints. Hyperuricemia is the fundamental factor of gout. The onset of hyperuricemia is …

Objective To evaluate the global burden of musculoskeletal (MSK) disorders, as well as the
five common conditions, and their relevant risk factors from 1990 to 2019. Design Data from …

Uric acid (UA) is the final product of purine metabolism in the human body, and impaired
purine metabolism can increase the uric acid in serum, finally resulting in hyperuricemia …

Homeostasis is a prerequisite for health. When homeostasis becomes disrupted, dysfunction
occurs. This is especially the case for the gut microbiota, which under normal conditions …

Gout is a chronic disease with inflammatory arthritis caused by monosodium urate (MSU)
crystals deposition, an elevated serum urate level (hyperuricaemia) is the critical factor …

Except for well-known commercial production procedures, this study demonstrates that
Ta2O5 particles can be produced. Through a series of steps, highly pure Ta2O5 particles …

Background Hyperuricemia (HUA) is characterized by abnormal serum uric acid (UA) levels
and demonstrated to be involved in renal injury leading to hyperuricemic nephropathy (HN) …

Introduction The urate transporter 1 (URAT1) is a membrane transporter located in the apical
membrane of human renal proximal tubule epithelial cells, which mediates most of the …

Hyperuricemia (HUA) affects human health and is involved in the pathogenesis of common
chronic diseases. Previous studies showed that Ganoderma lucidum extract lowered HUA in …