[HTML][HTML] Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy

L Cai, Y Li, J Tan, L Xu, Y Li - Journal of hematology & oncology, 2023 - Springer
In one decade, immunotherapy based on immune checkpoint blockades (ICBs) has become
a new pillar of cancer treatment following surgery, radiation, chemotherapy, and targeted …

[HTML][HTML] Nasopharyngeal carcinoma ecology theory: Cancer as multidimensional spatiotemporal “unity of ecology and evolution” pathological ecosystem

W Luo - Theranostics, 2023 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a particular entity of head neck cancer that is generally
regarded as a genetic disease with diverse intertumor and intratumor heterogeneity. This …

[HTML][HTML] Recent advances in targeted strategies for triple-negative breast cancer

S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

[HTML][HTML] Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatment

Z Gao, Y Bai, A Lin, A Jiang, C Zhou, Q Cheng, Z Liu… - Molecular Cancer, 2023 - Springer
As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

Dressing bacteria with a hybrid immunoactive nanosurface to elicit dual anticancer and antiviral immunity

Y Liu, M Zhang, X Wang, F Yang, Z Cao… - Advanced …, 2023 - Wiley Online Library
Approaches capable of simultaneously treating cancer and protecting susceptible patients
from lethal infections such as coronavirus disease 2019, are highly desirable but prove to be …

[HTML][HTML] Synergistic efficacy of simultaneous anti-TGF-β/VEGF bispecific antibody and PD-1 blockade in cancer therapy

M Niu, M Yi, Y Wu, L Lyu, Q He, R Yang, L Zeng… - Journal of Hematology & …, 2023 - Springer
Background Recently, therapeutic antibodies against programmed cell death 1 (PD-1) and
its ligand (PD-L1) have exerted potent anticancer effect in a variety of tumors. However …

Nanozyme-mediated biocatalysis as a mitochondrial oxidative stress amplifier for tumor nanocatalytic immunotherapy

J Lu, L Song, S Feng, K Wang, Y Mao, Y Gao… - Chemical Engineering …, 2024 - Elsevier
Nanozyme-mediated tumor catalytic therapy has recently garnered attention as a means of
destroying tumor cells and eliciting anti-tumor immune responses. Herein, a copper-doped …

[HTML][HTML] cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment

H Zhang, Y Liu, J Liu, J Chen, J Wang, H Hua… - Journal of Hematology & …, 2024 - Springer
Cancer is a complex disease resulting from abnormal cell growth that is induced by a
number of genetic and environmental factors. The tumor microenvironment (TME), which …

[HTML][HTML] Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas

GA Herrgott, JM Snyder, R She, TM Malta… - Nature …, 2023 - nature.com
Recurrence of meningiomas is unpredictable by current invasive methods based on
surgically removed specimens. Identification of patients likely to recur using noninvasive …

[HTML][HTML] Spatial transcriptomics: Technologies, applications and experimental considerations

Y Wang, B Liu, G Zhao, YJ Lee, A Buzdin, X Mu, J Zhao… - Genomics, 2023 - Elsevier
The diverse cell types of an organ have a highly structured organization to enable their
efficient and correct function. To fully appreciate gene functions in a given cell type, one …