AXL-TBK1 driven nuclear AKT3 promotes metastasis
Epithelial-to-mesenchymal transition (EMT) contributes to tumor cell survival, immune
evasion, migration, invasion, and therapy resistance. Across human cancer, tumors that are …
evasion, migration, invasion, and therapy resistance. Across human cancer, tumors that are …
Lrg1 inhibits the activation of hepatic macrophages to alleviate NAFLD by enhancing TGF-β1 signaling
L XU, J HAN, ZHE YANG, Y YANG, J CHEN, X WU… - 2022 - researchsquare.com
Background: Non-alcoholic fatty liver disease (NAFLD) is caused by excessive hepatic lipid
deposition, and is characterized by hepatocyte steatosis, the accumulation of immune cells …
deposition, and is characterized by hepatocyte steatosis, the accumulation of immune cells …
Deciphering AXL-Driven Molecular Mechanisms of EMT
EN Arner - 2021 - utswmed-ir.tdl.org
Cellular plasticity, a feature associated with epithelial-to-mesenchymal transition (EMT),
contributes to tumor cell survival, migration, invasion, and therapy resistance. Across human …
contributes to tumor cell survival, migration, invasion, and therapy resistance. Across human …
[引用][C] LRG1 抑制小鼠肝巨噬细胞活化从而改善代谢相关脂肪性肝病抑制小鼠肝巨噬细胞活化从而改善代谢相关脂肪性肝病: 基于增基于增强TGF-β1 信号通路
徐龙飞， 韩晶， 杨喆， 杨燕平， 陈金慧， 吴西军， 王琪… - europepmc.org
目的探讨肝细胞来源的富含亮氨酸α-2 糖蛋白1 (LRG1) 对M1 型肝巨噬细胞活化的影响.
方法BALB/c 小鼠通过高脂饮食(HFD) 喂养16 周来建立代谢相关脂肪性肝病(MAFLD) 模型 …
方法BALB/c 小鼠通过高脂饮食(HFD) 喂养16 周来建立代谢相关脂肪性肝病(MAFLD) 模型 …