Ethnic pharmacological relevance Pulmonary fibrosis (PF) is a fibrotic interstitial lung
disease caused by continuous damage and excessive repair of alveolar epithelial cells, the …

N-acetylcysteine (NAC) is widely used because of its mucolytic effects, taking part in the
therapeutic protocols of cystic fibrosis. NAC is also administered as an antidote in …

The “Thalidomide tragedy” is a landmark in the history of the pharmaceutical industry.
Despite limited clinical trials, there is a continuous effort to investigate thalidomide as a drug …

Idiopathic pulmonary fibrosis (IPF) is a fatal and irreversible disease with few effective
treatments. Alveolar macrophages (AMs) are involved in the development of IPF from the …

Background: Methotrexate (MTX) is an effective anticancer, anti-inflammatory, and
immunomodulatory agent. However, it induces a serious pneumonitis that leads to …

Pulmonary fibrosis (PF) is a feared component in over 200 interstitial pulmonary diseases,
which are characterized by increased alveolar wall thickness, excessive scarring, and …

Increasing evidence suggests that there is acceleration of lung ageing in chronic lung
diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary …

Pulmonary fibrosis (PF) threatens millions of people worldwide with its irreversible
progression. Although the underlying pathogenesis of PF is not fully understood, there is …

This study aimed to investigate the potential anti-fibrotic activity of vinpocetine in an
experimental model of pulmonary fibrosis by bleomycin and in the MRC-5 cell line …

Ocular tissue, especially the cornea, is overly sensitive to chemical exposures. The
availability and adoption of chemical threat agent chloropicrin (CP) is growing in the United …