[HTML][HTML] Leishmaniasis worldwide and global estimates of its incidence

J Alvar, ID Vélez, C Bern, M Herrero, P Desjeux… - PloS one, 2012 - journals.plos.org
As part of a World Health Organization-led effort to update the empirical evidence base for
the leishmaniases, national experts provided leishmaniasis case data for the last 5 years …

Advances in leishmaniasis

HW Murray, JD Berman, CR Davies, NG Saravia - The Lancet, 2005 - thelancet.com
Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

PCR diagnosis and characterization of Leishmania in local and imported clinical samples

G Schönian, A Nasereddin, N Dinse… - … and infectious disease, 2003 - Elsevier
Leishmaniasis diagnosis in regions where multiple species exist should identify each
species directly in the clinical sample without parasite culturing. The sensitivity of two PCR …

Laboratory diagnosis of visceral leishmaniasis

S Sundar, M Rai - Clinical and vaccine immunology, 2002 - Am Soc Microbiol
The group of diseases known as the leishmaniases are caused by obligate intracellular
protozoa of the genus Leishmania (39). Natural transmission of leishmania is carried out by …

Leishmania and the leishmaniases: a parasite genetic update and advances in taxonomy, epidemiology and pathogenicity in humans

AL Bañuls, M Hide, F Prugnolle - Advances in parasitology, 2007 - Elsevier
Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

[HTML][HTML] Spread of vector-borne diseases and neglect of Leishmaniasis, Europe

JC Dujardin, L Campino, C Cañavate… - Emerging infectious …, 2008 - ncbi.nlm.nih.gov
The risk for reintroduction of some exotic vector-borne diseases in Europe has become a hot
topic, while the reality of others is neglected at the public health policy level. Leishmaniasis …

Quantification of Leishmania infantum DNA by a Real-Time PCR Assay with High Sensitivity

C Mary, F Faraut, L Lascombe… - Journal of clinical …, 2004 - Am Soc Microbiol
ABSTRACT A real-time PCR was developed to quantify Leishmania infantum kinetoplast
DNA and optimized to reach a sensitivity of 0.0125 parasites/ml of blood. In order to analyze …

Comparison of six PCR methods using peripheral blood for detection of canine visceral leishmaniasis

L Lachaud, S Marchergui-Hammami… - Journal of clinical …, 2002 - Am Soc Microbiol
The objectives of this study were to compare the sensitivities and reliabilities of different
PCR methods for the diagnosis and epidemiological study of canine visceral leishmaniasis …

[HTML][HTML] Mechanisms of cellular invasion by intracellular parasites

DM Walker, S Oghumu, G Gupta, BS McGwire… - Cellular and molecular …, 2014 - Springer
Numerous disease-causing parasites must invade host cells in order to prosper.
Collectively, such pathogens are responsible for a staggering amount of human sickness …

[HTML][HTML] Study of Leishmania pathogenesis in mice: experimental considerations

C Loeuillet, AL Bañuls, M Hide - Parasites & vectors, 2016 - Springer
Although leishmaniases are endemic in 98 countries, they are still considered neglected
tropical diseases. Leishmaniases are characterized by the emergence of new virulent and …