A whole‐course‐repair system based on neurogenesis‐angiogenesis crosstalk and macrophage reprogramming promotes diabetic wound healing

Y Xiong, Z Lin, P Bu, T Yu, Y Endo, W Zhou… - Advanced …, 2023 - Wiley Online Library
Diabetic wound (DW) therapy is currently a big challenge in medicine and strategies to
enhance neurogenesis and angiogenesis have appeared to be a promising direction …

Antinuclear antibodies positivity in women in reproductive age: from infertility to adverse obstetrical outcomes–a meta-analysis

C Ticconi, A Inversetti, E Logruosso, M Ghio… - Journal of Reproductive …, 2023 - Elsevier
This systematic review and meta-analysis were designed to identify possible correlations
between isolated serum antinuclear antibody (ANA) and (i) infertility in the context of in-vitro …

Hydrogel-based dressings designed to facilitate wound healing

W Zhang, L Liu, H Cheng, J Zhu, X Li, S Ye, X Li - Materials Advances, 2024 - pubs.rsc.org
The escalating prevalence of wounds, particularly chronic wounds, poses significant
challenges in terms of treatment management and has led to an increase in healthcare …

Elevated branched-chain α-keto acids exacerbate macrophage oxidative stress and chronic inflammatory damage in type 2 diabetes mellitus

S Liu, L Li, P Lou, M Zhao, Y Wang, M Tang… - Free Radical Biology …, 2021 - Elsevier
Aims Chronic inflammation is a primary reason for type 2 diabetes mellitus (T2DM) and its
complications, while disordered branched-chain amino acids (BCAA) metabolism is found in …

P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss

C Ge, D Xu, P Yu, M Fang, J Guo, D Xu, Y Qiao… - BMC medicine, 2021 - Springer
Background Prenatal adverse environments can cause fetal intrauterine growth retardation
(IUGR) and higher susceptibility to multiple diseases after birth, related to multi-organ …

[HTML][HTML] Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism

J Cheng, Z Yang, XY Ge, MX Gao, R Meng, X Xu… - Cell Metabolism, 2022 - cell.com
Along with functionally intact insulin, diabetes-associated insulin peptides are secreted by β
cells. By screening the expression and functional characterization of olfactory receptors …

Uncovering the gene regulatory network of type 2 diabetes through multi-omic data integration

J Liu, S Liu, Z Yu, X Qiu, R Jiang, W Li - Journal of Translational Medicine, 2022 - Springer
Abstract Background Type 2 diabetes (T2D) onset is a complex, organized biological
process with multilevel regulation, and its physiopathological mechanisms are yet to be …

Maternal propionate supplementation ameliorates glucose and lipid metabolic disturbance in hypoxia-induced fetal growth restriction

D Chen, Y Wang, S Li, H Zhao, F Jiang, Y Wu… - Food & function, 2022 - pubs.rsc.org
Intrauterine growth restriction (IUGR), one of the major complications of pregnancy, is
characterized by low birth weight and results in higher risks for long-term problems including …

Identification of stable reference genes in peripheral blood mononuclear cells from type 2 diabetes mellitus patients

A Hazarika, B Nongkhlaw, A Mukhopadhyay - Scientific Reports, 2023 - nature.com
Reference genes are obligatory for accurate normalization of mRNA transcript levels across
samples and experimental conditions in Real Time-polymerase chain reaction (qRT-PCR) …

Exercise training-attenuated insulin resistance and liver injury in elderly pre-diabetic patients correlates with NLRP3 inflammasome

T Zhang, J Tian, J Fan, X Liu, R Wang - Frontiers in Immunology, 2023 - frontiersin.org
Background Diabetes is one of the most common metabolic diseases and continues to be a
leading cause of death worldwide. The NLRP3 inflammasome has been shown to exert …