Nanodiamonds: the intersection of nanotechnology, drug development, and personalized medicine
The implementation of nanomedicine in cellular, preclinical, and clinical studies has led to
exciting advances ranging from fundamental to translational, particularly in the field of …
exciting advances ranging from fundamental to translational, particularly in the field of …
Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases
Both communicable and non-communicable chronic respiratory conditions have accorded
for suffering of millions of people of all ages and stated to be leading cause of death …
for suffering of millions of people of all ages and stated to be leading cause of death …
Tiotropium and olodaterol fixed-dose combination versus mono-components in COPD (GOLD 2–4)
R Buhl, F Maltais, R Abrahams… - European …, 2015 - Eur Respiratory Soc
Efficacy and safety of tiotropium+ olodaterol fixed-dose combination (FDC) compared with
the mono-components was evaluated in patients with moderate to very severe chronic …
the mono-components was evaluated in patients with moderate to very severe chronic …
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
C Vogelmeier, B Hederer, T Glaab… - … England Journal of …, 2011 - Mass Medical Soc
Background Treatment guidelines recommend the use of inhaled long-acting
bronchodilators to alleviate symptoms and reduce the risk of exacerbations in patients with …
bronchodilators to alleviate symptoms and reduce the risk of exacerbations in patients with …
[HTML][HTML] Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with …
D Singh, PW Jones, ED Bateman, S Korn… - BMC pulmonary …, 2014 - Springer
Background Aclidinium/formoterol is a twice-daily (BID) fixed-dose combination (FDC) in
development for chronic obstructive pulmonary disease (COPD). The efficacy and safety of …
development for chronic obstructive pulmonary disease (COPD). The efficacy and safety of …
[HTML][HTML] Comparative efficacy of once-daily umeclidinium/vilanterol and tiotropium/olodaterol therapy in symptomatic chronic obstructive pulmonary disease: a …
GJ Feldman, AR Sousa, DA Lipson, L Tombs… - Advances in …, 2017 - Springer
Introduction We report the results of the first direct comparison of the once-daily fixed-dose
long-acting muscarinic antagonist/long-acting β 2-agonist (LAMA/LABA) combinations …
long-acting muscarinic antagonist/long-acting β 2-agonist (LAMA/LABA) combinations …
[HTML][HTML] Aclidinium bromide and formoterol fumarate as a fixed-dose combination in COPD: pooled analysis of symptoms and exacerbations from two six-month …
ED Bateman, KR Chapman, D Singh, AD D'Urzo… - Respiratory …, 2015 - Springer
Background The combination of aclidinium bromide, a long-acting anticholinergic, and
formoterol fumarate, a long-acting beta 2-agonist (400/12 μg twice daily) achieves …
formoterol fumarate, a long-acting beta 2-agonist (400/12 μg twice daily) achieves …
[HTML][HTML] Efficacy and safety of glycopyrrolate/formoterol metered dose inhaler formulated using co-suspension delivery technology in patients with COPD
Background Long-acting muscarinic antagonist (LAMA)/long-acting β 2-agonist (LABA)
combinations are a treatment option for patients with COPD who continue to have symptoms …
combinations are a treatment option for patients with COPD who continue to have symptoms …
[HTML][HTML] The 24-h lung-function profile of once-daily tiotropium and olodaterol fixed-dose combination in chronic obstructive pulmonary disease
KM Beeh, J Westerman, AM Kirsten, J Hébert… - Pulmonary …, 2015 - Elsevier
Background This study investigated the effects on 24-h lung function and lung volume of a
once-daily fixed-dose combination (FDC) of the long-acting muscarinic antagonist tiotropium …
once-daily fixed-dose combination (FDC) of the long-acting muscarinic antagonist tiotropium …
Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat® versus placebo and formoterol twice daily in patients with GOLD 2–4 …
A Koch, E Pizzichini, A Hamilton, L Hart… - … journal of chronic …, 2014 - Taylor & Francis
Two replicate, multicenter, randomized, double-blind, placebo-controlled, parallel-group,
Phase III studies investigated the long-term efficacy and safety of once-daily olodaterol via …
Phase III studies investigated the long-term efficacy and safety of once-daily olodaterol via …