[HTML][HTML] Neuroprotective effects of coffee bioactive compounds: a review

K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

[HTML][HTML] Natural Nrf2 activators from juices, wines, coffee, and cocoa

M Qader, J Xu, Y Yang, Y Liu, S Cao - Beverages, 2020 - mdpi.com
Juices, wine, coffee, and cocoa are rich sources of natural polyphenolic compounds that
have potent antioxidant activities proven by in vitro and in vivo studies. These polyphenolic …

Usnic acid induced changes in biomolecules and their association with apoptosis in squamous carcinoma (A-431) cells: A flow cytometry, FTIR and DLS spectroscopic …

M Kumari, S Kamat, C Jayabaskaran - Spectrochimica Acta Part A …, 2022 - Elsevier
Many natural products induce apoptotic cell death in cancer cells, though studies on their
interactions with macromolecules are limited. For the first time, this study demonstrated the …

Pretreatment with Kahweol Attenuates Sepsis‐Induced Acute Lung Injury via Improving Mitochondrial Homeostasis in a CaMKKII/AMPK‐Dependent Pathway

G Li, T Fu, W Wang, R Xiong, B Liu… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope It is well‐established that dysregulated mitochondrial homeostasis in macrophages
leads to inflammation, oxidative stress, and tissue damage, which are essential in the …

[HTML][HTML] The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen …

FB Brasil, RCB Gobbo, FJS de Almeida… - Neurochemistry …, 2021 - Elsevier
The mitochondria are the major source of reactive species in the mammalian cells.
Hydrogen peroxide (H 2 O 2) is a potent inducer of redox impairment by a mechanism, at …

[HTML][HTML] Effects of coffee on sirtuin-1, homocysteine, and cholesterol of healthy adults: does the coffee powder matter?

GHF Gonçalinho, JRO Nascimento, BM Mioto… - Journal of Clinical …, 2022 - mdpi.com
Background: Coffee is one of the most popular beverages globally and contains several
bioactive compounds that are relevant to human health. Many nutritional strategies …

[HTML][HTML] Addressing the Neuroprotective Actions of Coffee in Parkinson's Disease: An Emerging Nutrigenomic Analysis

LK Lee, NAR Mhd Rodzi - Antioxidants, 2022 - mdpi.com
Caffeine is one of the predominant dietary components and psychostimulants present in
coffee, a widely appreciated beverage. Corroborating epidemiological and laboratory …

[HTML][HTML] Systematic analysis of the molecular mechanisms mediated by coffee in Parkinson's disease based on network pharmacology approach

F Li, T Hatano, N Hattori - Journal of Functional Foods, 2021 - Elsevier
Many epidemiological studies have associated coffee consumption with a reduced
Parkinson's disease (PD) risk, but the molecular mechanisms remain unclear. In this study …

[HTML][HTML] Kahweol activates the Nrf2/HO-1 pathway by decreasing Keap1 expression independently of p62 and autophagy pathways

HY Seo, SH Lee, JH Lee, JS Hwang, MK Kim… - PLoS One, 2020 - journals.plos.org
Kahweol is a diterpene found in coffee beans and unfiltered coffee drinks. Several studies
have demonstrated that kahweol induces the nuclear factor erythroid-2 related factor …

Promotion of mitochondrial protection by emodin in methylglyoxal-treated human neuroblastoma SH-SY5Y cells: involvement of the AMPK/Nrf2/HO-1 axis

MR de Oliveira, ICC de Souza, FB Brasil - Neurotoxicity Research, 2021 - Springer
Mitochondrial dysfunction is part of the mechanism of several human diseases. This
negative circumstance may be induced by certain toxicants, as methylglyoxal (MG). MG is a …