Infertility has become a major health issue in the world. It affects the social life of couples
and of all infertility cases; approximately 40–50% is due to “male factor” infertility. Male …

Male germ cell development requires precise regulation of gene activity in a cell-type and
stage-specific manner, with perturbations in gene expression during spermatogenesis …

Background Spermatogenesis is one of the most complicated cellular differentiation
processes in a body. Researchers struggled to find and develop a micro‐environmental …

Apoptosis occurs at any time in the ontogeny of the testis, especially during the first wave of
spermatogenesis. However, the exact mechanisms by which homeostasis of apoptosis and …

Cadmium (Cd), one of the most common contaminants in diet and drinking water, impairs
testicular germ cell development and spermatogenesis. Autophagy is essential for …

Spermatogonial stem cells are quiescent, undergo self-renewal or differentiating divisions,
thereby forming the cellular basis of spermatogenesis. This cellular development is …

Retinoids are essential for reproduction. Most research has focused on the role of retinoic
acid signaling in the regulation of meiosis during early fetal germ cell development …

We hypothesised that antenatal exposure to ubiquitous phthalates may lead to an earlier
menarche and a lower prevalence of polycystic ovarian syndrome (PCOS) and polycystic …

We previously reported the successful induction and completion of mouse spermatogenesis
by culturing neonatal testis tissues. The culture medium consisted of α-minimum essential …

The male infertility of cattleyak resulted from spermatogenic arrest has greatly restricted the
effective utilization of the heterosis from crossbreeding of cattle and yak. Based on our …