Alzheimer's disease (AD) is a neurodegenerative disease that causes late-onset dementia.
The R47H variant of the microglial receptor TREM2 triples AD risk in genome-wide …

Traumatic brain injury (TBI) is a chronic and debilitating disease, associated with a high risk
of psychiatric and neurodegenerative diseases. Despite significant advancements in …

Clinical trials of therapeutics for traumatic brain injury (TBI) demonstrating preclinical efficacy
for TBI have failed to replicate these results in humans, in part due to the absence of …

Traumatic brain injury is a major source of global disability and mortality. Preclinical TBI
models are a crucial component of therapeutic investigation. We report a tunable, monitored …

Damage to the axonal white matter tracts within the brain is a key cause of neurological
impairment and long-term disability following traumatic brain injury (TBI). Understanding …

Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and
its mild severity represents the most frequent cases. Moderate and severe injuries as well as …

Hypoxemia during initial stabilization of patients with severe traumatic brain injury (TBI) has
been associated with poorer outcomes. However, the effects of delayed hypoxemia …

Appropriate rehabilitation of stroke patients at a very early phase results in favorable
outcomes. However, the optimal strategy for very early rehabilitation is at present unclear …

Therapeutic interventions targeting secondary insults, such as delayed hypoxemia, provide
a unique opportunity for treatment in severe traumatic brain injury (TBI). Erythropoietin (EPO) …

Traumatic brain injury (TBI) can result in axonal loss and demyelination, leading to
persistent damage in the white matter. Demyelinated axons are vulnerable to pathologies …