The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Early gene therapy studies held great promise for the cure of heritable diseases, but the
occurrence of various genotoxic events led to a pause in clinical trials and a more guarded …

Abstract Background The novel endonuclease Cas12b was engineered for targeted
genome editing in mammalian cells and is a promising tool for certain applications because …

Combination antiretroviral therapy (cART) has significantly improved the prognosis of
individuals living with human immunodeficiency virus (HIV). Acquired immunodeficiency …

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated enzyme-
CAS holds great promise for treating many uncured human diseases and illnesses by …

CRISPR/Cas9 technology is expected to offer novel genome editing-related therapies for
various diseases. We previously showed that an adenovirus vector (AdV) possessing eight …

Extracellular vesicles (EVs), these minute yet mighty cellular messengers are redefining our
understanding of a spectrum of diseases, from cancer to cardiovascular ailments …

Background HIV infection and its progression to AIDS depend on several factors including
host genetic factors. The immunological mechanisms of host resistance to HIV infection …

Chemokines are cytokines whose primary role is cellular activation and stimulation of
leukocyte migration. They perform their various functions by interacting with G protein …

Genome editing using the CRISPR/Cas system has revolutionized the field of genetic
engineering, offering unprecedented opportunities for therapeutic applications in vivo …