Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

The great escape: how cationic polyplexes overcome the endosomal barrier

T Bus, A Traeger, US Schubert - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Mimicking the cell: bio-inspired functions of supramolecular assemblies

Y Tu, F Peng, A Adawy, Y Men… - Chemical …, 2016 - ACS Publications
The successful assembly of large supramolecular structures infers a delicate balance
between reversible noncovalent interactions which are capable of undergoing correction …

Biomimetic catalysis

L Marchetti, M Levine - ACS Catalysis, 2011 - ACS Publications
The field of biomimetic chemistry encompasses a wide variety of subfields, including
biomimetic catalysis, bioinspired self-assembly, and biomimetic reactions in total synthesis …

Dynamic multi-level microstructured antifouling surfaces by combining quaternary ammonium modified GO with self-polishing copolymers

J Sha, R Chen, J Yu, Q Liu, J Liu, J Zhu, P Liu, R Li… - Carbon, 2023 - Elsevier
Marine biological fouling is the undesirable accumulation on the surfaces of submerged
objects and causes environmental and economic consequence to ships and marine …

Polycation architecture and assembly direct successful gene delivery: micelleplexes outperform polyplexes via optimal DNA packaging

Z Tan, Y Jiang, W Zhang, L Karls… - Journal of the …, 2019 - ACS Publications
Cellular delivery of biomacromolecules is vital to medical research and therapeutic
development. Cationic polymers are promising and affordable candidate vehicles for these …

A molecular thermodynamic model of complexation in mixtures of oppositely charged polyelectrolytes with explicit account of charge association/dissociation

A Salehi, RG Larson - Macromolecules, 2016 - ACS Publications
Into an extended Voorn–Overbeek (EVO) free energy model of polyelectrolyte (PE)
complexation and phase behavior, we incorporate three classes of short-ranged …

Polymeric siRNA gene delivery–transfection efficiency versus cytotoxicity

A Kargaard, JPG Sluijter, B Klumperman - Journal of controlled release, 2019 - Elsevier
Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …

[HTML][HTML] Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes

YY Won, R Sharma, SF Konieczny - Journal of Controlled Release, 2009 - ncbi.nlm.nih.gov
In about 70% of over 1,400 gene therapy clinical trials that have been conducted to date
worldwide, genetically-modified viruses have been the carrier of choice for delivery of …

Iron carbonyl compounds with aromatic dithiolate bridges as organometallic mimics of [FeFe] hydrogenases

S Gao, Y Liu, Y Shao, D Jiang, Q Duan - Coordination Chemistry Reviews, 2020 - Elsevier
Recently, substantial efforts had been made in the field of synthetic iron compounds as
structural and functional models of the hydrogenase enzyme active site for the purpose of …